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Effects of Exercise and Angiotensin-Converting Enzyme (ACE) on Aortic Stiffness in the Elderly

Sagiv, Moran, Eynon, Nir, Sagiv, Michael, Yamin, Chen and Alves, Alberto Jorge (2010) Effects of Exercise and Angiotensin-Converting Enzyme (ACE) on Aortic Stiffness in the Elderly. Archives of Exercise in Health and Disease, 1 (1). pp. 3-11. ISSN 1647-1652

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Senescence is a complex process involving many variables including genetics, lifestyle factors, and chronic diseases, the interaction of which significantly influences the manner in which we age (2). In particular, hypertension and genes of the rennin-angiotensin-aldosterone system have been associated with functional and structural changes of the large arteries, which are thought to contribute to age-related increases in the incidence of cardiovascular disease. Despite mounting evidence implicating sedentary behavior as a significant risk factor in chronic-disease morbidity and mortality among the elderly, there is a limited amount of information on the role of exercise in promoting optimal health and function in older people (27). The purpose of the present review is to discuss the effects of exercise training and angiotensin-converting enzyme (ACE) on aortic stiffness in the elderly.

Item Type: Article
Additional Information:

Review manuscript

Uncontrolled Keywords: ResPubID25143, aortic elasticity, angiotensin-converting enzyme, hypertension, genotype, exercise
Subjects: FOR Classification > 1102 Cardiorespiratory Medicine and Haematology
FOR Classification > 1106 Human Movement and Sports Science
Faculty/School/Research Centre/Department > Institute of Sport, Exercise and Active Living (ISEAL)
Depositing User: VUIR
Date Deposited: 29 Nov 2012 00:05
Last Modified: 22 Jan 2014 23:32
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