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A fast and mild method for the nitration of aromatic rings
Bak, Radoslaw and Smallridge, Andrew John (2001) A fast and mild method for the nitration of aromatic rings. Tetrahedron letters, 42 (38). pp. 6767-6769. ISSN 0040-4039
Full text for this resource is not available from the Research Repository.Abstract
The use of N2O5 and a Fe(III) catalyst for the nitration of aromatic rings is described. This methodology is compatible with most functional groups and results in near quantitative yields in 4 min. The reaction conditions are non-oxidising: benzaldehyde and benzyl alcohols are readily nitrated with little or no oxidation (<4%) occurring. The addition of the iron catalyst activates the system to such an extent that nitration of an activated aromatic ring, such as toluene, occurs quantitatively at −100°C. This high activity allows compounds with sensitive functional groups such as alkenes to be smoothly nitrated.
Item Type: | Article |
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Uncontrolled Keywords: | aromatic rings, methodology, N2O5, Fe(III) |
Subjects: | Historical > RFCD Classification > 290000 Engineering and Technology Historical > Faculty/School/Research Centre/Department > School of Engineering and Science |
Depositing User: | Ms Phung T Tran |
Date Deposited: | 20 Oct 2008 22:05 |
Last Modified: | 16 Oct 2010 02:11 |
URI: | http://vuir.vu.edu.au/id/eprint/1098 |
DOI: | https://doi.org/10.1016/S0040-4039(01)01378-8 |
ePrint Statistics: | View download statistics for this item |
Citations in Scopus: | 73 - View on Scopus |
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