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Sprint training reduces urinary purine loss following intense exercise in humans

Stathis, Christos George and Carey, Michael F and Hayes, Alan and Garnham, Andrew P and Snow, Rodney J (2005) Sprint training reduces urinary purine loss following intense exercise in humans. Applied Physiology, Nutrition & Metabolism, 31 (6). pp. 702-708. ISSN 1715-5320

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Abstract

The influence of sprint training on endogenous urinary purine loss was examined in seven active male subjects (age: 23.1 ± 1.8 years, weight: 76.1 ± 3.1 kg, VO2peak: 56.3 ± 4.0 ml.kg-1.min-1). Each subject performed a 30s sprint performance test (PT), before and after 7 days of sprint training. Training consisted of fifteen 10s sprints on an air-braked cycle ergometer performed twice per day. A rest period of 50s separated each sprint during training. Sprint training resulted in a 20% higher muscle ATP immediately after PT, a lower IMP (57% and 89%, immediately following and after 10 min recovery from PT, respectively), and inosine accumulation (53% and 56%, immediately following and 10 min after the PT, respectively). Sprint training also attenuated the exercise-induced increases in plasma inosine, hypoxanthine (Hx) and uric acid during the first 120 min of recovery and reduced the total urinary excretion of purines (inosine + Hx + uric acid) in the 24 hours recovery following intense exercise. These results show that intermittent sprint training reduces the total urinary purine excretion after a 30s sprint bout.

Item Type: Article
Uncontrolled Keywords: hypoxanthine, inosine, metabolism, sprint training, uric acid
Subjects: RFCD Classification > 320000 Medical and Health Sciences
Faculty/School/Research Centre/Department > School of Biomedical and Health Sciences
Depositing User: Ms Marcia Millard
Date Deposited: 14 Oct 2008 03:42
Last Modified: 11 Feb 2015 05:25
URI: http://vuir.vu.edu.au/id/eprint/1337
DOI: 10.1139/h06-074
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Citations in Scopus: 7 - View on Scopus

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