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Skeletal muscle structure and metabolism in chronic heart failure

Williams, Andrew Dafydd (2005) Skeletal muscle structure and metabolism in chronic heart failure. PhD thesis, Victoria University of Technology.

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Abstract

Chronic heart failure (CHF) patients have poor exercise tolerance, which does not correlate with impaired central function. Consequently factors other than impaired cardiac function must contribute to the exercise intolerance. Maladaptations in skeletal muscle appear to be a likely reason for the limited exercise tolerance. In study I, exercise tolerance and skeletal muscle metabolism and morphology were examined in 17 CHF patients and eight healthy similarly aged sedentary control subjects. In Study II, thirteen CHF patients participated in a study on the effects of resistance training on exercise tolerance and skeletal muscle morphology and metabolism.

Item Type: Thesis (PhD thesis)
Uncontrolled Keywords: Heart failure, Muscles, Exercise therapy
Subjects: FOR Classification > 1102 Cardiovascular Medicine and Haematology
FOR Classification > 1101 Medical Biochemistry and Metabolomics
Faculty/School/Research Centre/Department > School of Biomedical and Health Sciences
Depositing User: VU Library
Date Deposited: 02 Aug 2010 22:33
Last Modified: 23 May 2013 16:44
URI: http://vuir.vu.edu.au/id/eprint/15730
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