Yeast-based process for production of I-pac
Smallridge, Andrew John, Trewhella, Maurice Arthur, Wilkinson, Kylie Anne (2006) Yeast-based process for production of I-pac. United States Patent 7063969.Full text for this resource is not available from the Research Repository.
The invention provides a method of synthesis of a substituted or unsubstituted carbinol compound, comprising the steps of subjecting the corresponding substituted or unsubstituted aromatic aldehyde to acyloin condensation mediated by yeast in the presence of either (a) a supereritical fluid or (b) a liquefied gas, and recovering the carbinol compound. Preferably the yeast is Saccharomyces cerevisiae. In a particularly preferred embodiment the aromatic aldehyde is benzaldehyde and the carbinol is phenylacetylcarbinol, according to the reaction (I): in which the benzaldehyde, the pyruvic acid, or both may optionally be substituted.
|Uncontrolled Keywords:||yeast-based, i-pac, USP 7063969, supereritical fluid, liquefied gas|
|Subjects:||RFCD Classification > 290000 Engineering and Technology
Faculty/School/Research Centre/Department > School of Engineering and Science
|Depositing User:||Ms Phung T Tran|
|Date Deposited:||12 Nov 2008 22:38|
|Last Modified:||16 Oct 2010 02:34|
|DOI:||United States Patent 7063969|
|ePrint Statistics:||View download statistics for this item|
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