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Doxorubicin: an update on anticancer molecular action, toxicity and novel drug delivery systems

Tacar, Oktay, Sriamornsak, Pornsak and Dass, Crispin R (2013) Doxorubicin: an update on anticancer molecular action, toxicity and novel drug delivery systems. Journal of Pharmacy and Pharmacology, 65 (2). pp. 157-170. ISSN 0022-3573 (print) 2042-7158 (online)

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Abstract

The frontline drug doxorubicin has been used for treating cancer for over 30 years. While providing a cure in select cases, doxorubicin causes toxicity to most major organs, especially life-threate ning cardiotoxicity, which forces the treatment to become dose-limiting.

Item Type: Article
Uncontrolled Keywords: ResPubID26676, ResPubID25795, cancer, cardiotoxicity, chemotherapy, doxorubicin, drugs, pharmaceuticals
Subjects: Faculty/School/Research Centre/Department > School of Biomedical and Health Sciences
FOR Classification > 1112 Oncology and Carcinogenesis
FOR Classification > 1115 Pharmacology and Pharmaceutical Sciences
Depositing User: Ms Phung.T Tran
Date Deposited: 18 Jul 2014 05:46
Last Modified: 18 Jul 2014 05:52
URI: http://vuir.vu.edu.au/id/eprint/23703
DOI: https://doi.org/10.1111/j.2042-7158.2012.01567.x
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Citations in Scopus: 838 - View on Scopus

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