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Induced Metabolic Alkalosis Affects Muscle Metabolism and Repeated-Sprint Ability

Bishop, David, Edge, Johann, Davis, Cindy and Goodman, Carmel (2004) Induced Metabolic Alkalosis Affects Muscle Metabolism and Repeated-Sprint Ability. Medicine and Science in Sports and Exercise , 36 (5). pp. 807-813. ISSN 0195-9131 (print) 1530-0315 (online)

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Abstract

BISHOP, D., J. EDGE, C. DAVIS, and C. GOODMAN. Induced Metabolic Alkalosis Affects Muscle Metabolism and Repeated-Sprint Ability. Med. Sci. Sports Exerc., Vol. 36, No. 5, pp. 807–813, 2004. Purpose: The purpose of this study was to assess the effects of induced metabolic alkalosis, via sodium bicarbonate (NaHCO3) ingestion, on muscle metabolism and power output during repeated short-duration cycle sprints. Methods: Ten active females (mean ± SD: age = 19 ± 2 yr, [latin capital V with dot above]O2max = 41.0 ± 8.8 mL·kg -1·min -1) ingested either 0.3 g·kg -1 NaHCO3 or 0.207 g·kg -1 of NaCl (CON), in a double-blind, random, counterbalanced order, 90 min before performing a repeated-sprint ability (RSA) test (5 × 6-s all-out cycle sprints every 30 s). Results: Compared with CON, there was a significant increase in resting blood bicarbonate concentration [HCO3-] (23.6 ± 1.1 vs 30.0 ± 3.0 mmol·L -1) and pH (7.42 ± 0.02 vs 7.50 ± 0.04), but no significant difference in resting lactate concentration [La-] (0.8 ± 0.2 vs 0.8 ± 0.3 mmol·L -1) during the NaHCO3 trial. Muscle biopsies revealed no significant difference in resting muscle [La-], pH, or buffer capacity ([beta]in vitro) between trials (P > 0.05). Compared with CON, the NaHCO3 trial resulted in a significant increase in total work (15.7 ± 3.0 vs 16.5 ± 3.1 kJ) and a significant improvement in work and power output in sprints 3, 4, and 5. Despite no significant difference in posttest muscle pH between conditions, the NaHCO3 trial resulted in significantly greater posttest muscle [La-]. Conclusions: As NaHCO3 ingestion does not increase resting muscle pH or [beta]in vitro, it is likely that the improved performance is a result of the greater extracellular bufferconcentration increasing H+ efflux from the muscles into the blood. The significant increase in posttest muscle [La-] in NaHCO3 suggests that an increased anaerobic energy contribution is one mechanism by which NaHCO3 ingestion improved RSA.

Item Type: Article
Uncontrolled Keywords: buffer capacity, cycling, intermittent, exercise, team sports
Subjects: FOR Classification > 1106 Human Movement and Sports Science
Faculty/School/Research Centre/Department > School of Sport and Exercise Science
Depositing User: VUIR
Date Deposited: 13 Jan 2014 04:54
Last Modified: 22 Jan 2014 04:58
URI: http://vuir.vu.edu.au/id/eprint/24240
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Citations in Scopus: 144 - View on Scopus

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