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Effects of training on potassium, calcium and hydrogen ion regulation in skeletal muscle and blood during exercise

McKenna, Michael ORCID: 0000-0001-9998-0093, Harmer, Alison R, Fraser, Steve F and Li, Jia Li (1996) Effects of training on potassium, calcium and hydrogen ion regulation in skeletal muscle and blood during exercise. Acta Physiologica Scandinavica, 156 (3). pp. 335-346. ISSN 0001-6772

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Abstract

Ionic regulation is critical to muscle excitation, contraction and metabolism, and thus for muscle function during exercise. This review focuses on the effects of training upon K+, Ca2+ and H+ ion regulation in muscle and K+ regulation in blood during exercise. Training enhances K+ regulation in muscle and blood and reduces muscular fatiguability. Endurance, sprint and strength training in humans induce an increased muscle Na+, K+ pump concentration, usually associated with a reduced rise in plasma [K+] during exercise. Although impaired muscle Ca2+ regulation plays a vital role in fatigue, little is known about possible training effects. In rat fast-twitch muscle, overload-induced hypertrophy and endurance training were associated with reduced sarcoplasmic reticulum Ca2+ uptake, consistent with fast-to-slow fibre transition. In human muscle, endurance and strength training had no effect on muscle Ca2+ ATPase concentration. Whilst muscle Ca2+ uptake, release and Ca2+ ATPase activity were depressed by fatigue, no differences were found between strength athletes and untrained individuals. Muscle H+ accumulation may contribute to fatigue during intense exercise and is also modified by sprint training. Sprint training may increase muscle Lac- and work output with exhaustive exercise, but the rise in muscle [H+] is unchanged or attenuated, indicating a reduced rise in muscle [H+] relative to work performed. Muscle buffering capacity can be dissociated from this improved H+ regulatory capacity after training. Thus, training enhances muscle and blood K+ and muscle H+ regulation during exercise, consistent with improved muscular performance and reduced fatiguability; however, little is known about training effects on muscle Ca2+ regulation during contraction.

Item Type: Article
Uncontrolled Keywords: acidosis, K+, Ca2+, fatigue, hyperkalaemia, ion regulation, skeletal muscle function, training
Subjects: Current > FOR Classification > 1106 Human Movement and Sports Science
Historical > Faculty/School/Research Centre/Department > Institute of Sport, Exercise and Active Living (ISEAL)
Depositing User: VUIR
Date Deposited: 09 May 2014 04:12
Last Modified: 16 Apr 2019 07:34
URI: http://vuir.vu.edu.au/id/eprint/24808
DOI: https://doi.org/10.1046/j.1365-201X.1996.199000.x
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Citations in Scopus: 44 - View on Scopus

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