Soy protein ingestion results in less prolonged p70S6 kinase phosphorylation compared to whey protein after resistance exercise in older men

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Mitchell, CJ, Della Gatta, PA, Petersen, Aaron ORCID: 0000-0003-1508-748X, Cameron-Smith, D and Markworth, JF (2015) Soy protein ingestion results in less prolonged p70S6 kinase phosphorylation compared to whey protein after resistance exercise in older men. Journal of the International Society of Sports Nutrition, 12. ISSN 1550-2783

Abstract

Background The phosphorylation of p70S6 Kinase (p70S6K) is an important step in the initiation of protein translation. p70S6K phosphorylation is enhanced with graded intakes of whey protein after resistance exercise. Soy protein ingestion results in lower muscle protein synthesis after exercise compared with whey; however, the underlying mechanisms responsible for this difference have not been reported. Findings 13 older men (60–75) completed an acute bout of lower body resistance exercise and ingested 30 g of soy protein or carbohydrate. Muscle biopsies were obtained in the rested and fasted state and 2 and 4 hours post exercise. Phosphorylation status of p70S6K was measured with western blot. Results were compared with previously reported data from the ingestion of 30 g of whey protein or placebo. p70S6K phosphorylation was increased 2, but not 4 hours post exercise with soy protein ingestion. p70S6K phosphorylation was not increased post exercise with carbohydrate ingestion. Conclusions Ingesting 30 g of either whey or soy protein resulted in equivalent p70S6K phosphorylation at 2 hours post exercise, however, unlike whey, soy protein failed to promote prolonged phosphorylation of p70S6K to 4 hours post-exercise.

Item type Article
URI http://vuir.vu.edu.au/id/eprint/31781
Identification Number https://doi.org/10.1186/s12970-015-0070-2
Official URL http://jissn.biomedcentral.com/articles/10.1186/s1...
Subjects Current > FOR Classification > 1106 Human Movement and Sports Science
Current > FOR Classification > 1111 Nutrition and Dietetics
Historical > Faculty/School/Research Centre/Department > Institute of Sport, Exercise and Active Living (ISEAL)
Current > Division/Research > College of Sports and Exercise Science
Keywords Anabolic signalling; Supplementation; Aging; Sarcopenia
Citations in Scopus 20 - View on Scopus
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