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Soy protein ingestion results in less prolonged p70S6 kinase phosphorylation compared to whey protein after resistance exercise in older men

Mitchell, CJ, Della Gatta, PA, Petersen, Aaron ORCID: 0000-0003-1508-748X, Cameron-Smith, D and Markworth, JF (2015) Soy protein ingestion results in less prolonged p70S6 kinase phosphorylation compared to whey protein after resistance exercise in older men. Journal of the International Society of Sports Nutrition, 12. ISSN 1550-2783

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Abstract

Background The phosphorylation of p70S6 Kinase (p70S6K) is an important step in the initiation of protein translation. p70S6K phosphorylation is enhanced with graded intakes of whey protein after resistance exercise. Soy protein ingestion results in lower muscle protein synthesis after exercise compared with whey; however, the underlying mechanisms responsible for this difference have not been reported. Findings 13 older men (60–75) completed an acute bout of lower body resistance exercise and ingested 30 g of soy protein or carbohydrate. Muscle biopsies were obtained in the rested and fasted state and 2 and 4 hours post exercise. Phosphorylation status of p70S6K was measured with western blot. Results were compared with previously reported data from the ingestion of 30 g of whey protein or placebo. p70S6K phosphorylation was increased 2, but not 4 hours post exercise with soy protein ingestion. p70S6K phosphorylation was not increased post exercise with carbohydrate ingestion. Conclusions Ingesting 30 g of either whey or soy protein resulted in equivalent p70S6K phosphorylation at 2 hours post exercise, however, unlike whey, soy protein failed to promote prolonged phosphorylation of p70S6K to 4 hours post-exercise.

Item Type: Article
Uncontrolled Keywords: Anabolic signalling; Supplementation; Aging; Sarcopenia
Subjects: FOR Classification > 1106 Human Movement and Sports Science
FOR Classification > 1111 Nutrition and Dietetics
Faculty/School/Research Centre/Department > Institute of Sport, Exercise and Active Living (ISEAL)
Faculty/School/Research Centre/Department > College of Sports and Exercise Science
Depositing User: Symplectic Elements
Date Deposited: 11 Oct 2016 06:17
Last Modified: 03 May 2017 02:52
URI: http://vuir.vu.edu.au/id/eprint/31781
DOI: https://doi.org/10.1186/s12970-015-0070-2
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Citations in Scopus: 13 - View on Scopus

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