Cord Blood-Derived Mesenchymal Stem Cell Does Not Stimulate Nor Inhibits T Lymphocytes Activation
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Tong, C, Seow, Heng and Ramasamy, R (2008) Cord Blood-Derived Mesenchymal Stem Cell Does Not Stimulate Nor Inhibits T Lymphocytes Activation. The Medical Journal of Malaysia, 63 (July - Suppl A). pp. 77-78. ISSN 0300-5283
Abstract
The immune modulatory properties of mesenchymal stem cell (MSC) had brought a new insight in cell-based neotherapy. However, recent works of MSC are focused exclusively on bone marrow-derived MSC. We evaluated the immunogenicity of cord blood-derived MSC (CB-MSC) on T lymphocytes. Human peripheral blood mononuclear cells (PBMC) were prepared by density gradient separation and culture with the presence or absence of CB-MSC. PBMC were collected for activation analysis by flow cytometry at 24-, 48-, and 72- hours. The results showed that, CB-MSC does not stimulate nor inhibit T lymphocyte activation.
| Item type | Article |
| URI | https://vuir.vu.edu.au/id/eprint/4005 |
| Subjects | Historical > Faculty/School/Research Centre/Department > School of Biomedical and Health Sciences Historical > FOR Classification > 1107 Immunology Historical > SEO Classification > 970111 Expanding Knowledge in the Medical and Health Sciences |
| Keywords | ResPubID15906. T-lymphocytes, mesenchymal, stem cells, mesenchymal stem cells, neotherapy, peripheral blood mononuclear cells |
| Citations in Scopus | 6 - View on Scopus |
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