Research Repository

Probiotics-from Metchnikoff to Bioactives

Vasiljevic, Todor and Shah, Nagendra P (2008) Probiotics-from Metchnikoff to Bioactives. International Dairy Journal, 18 (7). pp. 714-728. ISSN 0958-6946

Full text for this resource is not available from the Research Repository.


The benefits of probiotics have been recognized and explored for over a century. The pioneering work of Tissier and Moro was elaborated in the Metchnikoff's theory of longevity and converted into commercial reality by Shirota and Kellogg in 1930s and German nutritionists with their probiotic therapy in 1950s. Our knowledge about probiotics and their interactions with the host has grown ever since and many potential and even proven mechanisms of action for probiotics have recently been published. Definitely, there is enough clinical evidence to support certain health claims attributed to selected strains of Lactobacillus and Bifidobacterium spp. However, substantial work needs to be done to substantiate other potentially beneficial properties including immunomodulation, hypocholesterolemic and anticarcinogenic effects. The aim of this review is to pay the tribute to pioneers in the field and provide an overview of the current state of knowledge about probiotics and their impact on our well-being.

Item Type: Article
Uncontrolled Keywords: ResPubID15468. probiotics, bioactives, Metchnikoff, nutritionalists, probiotic dairy products, lactic acid bacteria, probiotic foods, lactose intolerance, diarrhoea, allergies, modulation of the immune system, inflammatory bowel disease, intestinal pathogens, Helicobacter pylori, cholesterol, mutagenic, carcinogenic, hypocholesterolemic effect
Subjects: Historical > Faculty/School/Research Centre/Department > Institute for Sustainability and Innovation (ISI)
Current > FOR Classification > 0908 Food Sciences
Historical > SEO Classification > 8602 Dairy Products
Depositing User: VUIR
Date Deposited: 04 Aug 2011 05:41
Last Modified: 04 Aug 2011 05:41
ePrint Statistics: View download statistics for this item
Citations in Scopus: 281 - View on Scopus

Repository staff only

View Item View Item

Search Google Scholar