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Carrier-mediated delivery of peptidic drugs for cancer therapy

Dass, Crispin R and Choong, Peter F. M (2006) Carrier-mediated delivery of peptidic drugs for cancer therapy. Peptides, 27 (11). pp. 3020-3028. ISSN 0196-9781

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Abstract

Protein and peptide drugs are used for treatment of a variety of ailments. However, their wider use has been hindered by issues such as poor bioavailability in vivo and the cost involved in producing these drugs. This review discusses the various carrier-mediated methods used for delivery of peptide and protein drugs, with emphasis on liposomal and microspherical drug delivery systems. A brief look at the types of peptidic drugs currently in use clinically, and a brief discourse on several novel ideas for better protein delivery systems for cancer therapy is included.

Item Type: Article
Uncontrolled Keywords: ResPubID21890. peptides, peptide drugs, protein, drug delivery, cancer, liposome, microparticles
Subjects: Faculty/School/Research Centre/Department > School of Biomedical and Health Sciences
FOR Classification > 1112 Oncology and Carcinogenesis
SEO Classification > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions)
Depositing User: VUIR
Date Deposited: 21 Oct 2011 02:49
Last Modified: 19 Jun 2014 06:28
URI: http://vuir.vu.edu.au/id/eprint/7517
DOI: 10.1016/j.peptides.2006.05.020
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Citations in Scopus: 26 - View on Scopus

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