Research Repository

Impact of the neuroendocrine system on thymus and bone marrow function

Barnard, Adele and Layton, Daniel and Hince, Melanie and Sakkal, Samy and Bernard, Claude A and Chidgey, Ann P and Boyd, Richard L (2008) Impact of the neuroendocrine system on thymus and bone marrow function. Neuroimmunomodulation, 15 (1). pp. 7-18. ISSN 1021-7401

Full text for this resource is not available from the Research Repository.

Abstract

The nervous, endocrine, and immune systems interact to adapt to infection, inflammation, and tissue injury. Neural control is mediated in several ways, one of them being through the neuroendocrine regulation of the secretion of hypothalamic and pituitary hormones. The hormonal effects on the immune system range from the impact of steroidal hormones, which exhibit inhibitory effects over immune functions, to growth hormone, prolactin and neurohypophyseal hormones, known to stimulate and modulate humoral and cellular aspects of the immune system. This review will discuss the mechanisms behind the immunomodulatory role of the neuroendocrine system, including the critically important feedback loops required to maintain balance for these bidirectional interactions and alterations that occur with age.

Item Type: Article
Additional Information:

Online ISSN: 1423-0216

Uncontrolled Keywords: ResPubID22583. neuroendocrine system, endocrine system, nervous system, thymus, bone marrow, immune system, thymus, testosterone, estrogen, prolactin, progesterone, growth hormones, glucocorticoid, neurosecretory systems
Subjects: Faculty/School/Research Centre/Department > School of Biomedical and Health Sciences
FOR Classification > 1103 Clinical Sciences
Related URLs:
Depositing User: VUIR
Date Deposited: 11 Apr 2012 05:59
Last Modified: 29 Jan 2015 05:13
URI: http://vuir.vu.edu.au/id/eprint/7831
DOI: 10.1159/000135619
ePrint Statistics: View download statistics for this item
Citations in Scopus: 13 - View on Scopus

Repository staff only

View Item View Item

Search Google Scholar