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A novel twist to protein secretion in eukaryotes

Zimmermann, R and Blatch, Gregory L (2009) A novel twist to protein secretion in eukaryotes. Trends in Parasitology, 25 (4). pp. 147-150. ISSN 1471-4922 (print) 1471-5007 (online)

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Abstract

A recent functional analysis of the protein translocase, which is present in the trypanosomal endoplasmic reticulum membrane, by Michaeli and co-workers has indicated an unexpected diversity in the mechanisms and components of protein secretion in eukaryotes and might eventually pave the way for the development of anti-trypanosomal drugs. Furthermore, the work on these human parasites also supports conclusions that were drawn previously for components of protein secretion in human cells on the basis of in vitro studies.

Item Type: Article
Uncontrolled Keywords: ResPubID22195, proteins, eukaryotic cells, endoplasmic reticulum, anti-trypanosomal drugs
Subjects: Faculty/School/Research Centre/Department > School of Biomedical and Health Sciences
FOR Classification > 1004 Medical Biotechnology
FOR Classification > 1101 Medical Biochemistry and Metabolomics
Depositing User: VUIR
Date Deposited: 12 Jul 2012 23:52
Last Modified: 12 Jul 2012 23:52
URI: http://vuir.vu.edu.au/id/eprint/8141
DOI: https://doi.org/10.1016/j.pt.2009.01.002
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Citations in Scopus: 11 - View on Scopus

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