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Abnormal dose-response melatonin suppression by light in bipolar type I patients compared with healthy adult subjects

Hallam, Karen, Begg, Denovan P, Olver, James S and Norman, Trevor R (2009) Abnormal dose-response melatonin suppression by light in bipolar type I patients compared with healthy adult subjects. Acta Neuropsychiatrica, 21 (5). pp. 246-255. ISSN 0924-2708 (print) 1601-5215 (online)

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Abstract

Among potential endophenotypes proposed for bipolar affective disorder focusing on circadian abnormalities associated with the illness has particularly high face validity. Melatonin sensitivity to light is one circadian endophenotype proposed as useful in bipolar disorder. The aim of this study was to investigate melatonin sensitivity to light over a range of light intensities in order to compare and contrast responses in bipolar I patients with those of healthy adult volunteers.

Item Type: Article
Uncontrolled Keywords: ResPubID19563. biological markers, bipolar disorder, eye, depression
Subjects: Faculty/School/Research Centre/Department > School of Social Sciences and Psychology
FOR Classification > 1103 Clinical Sciences
SEO Classification > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions)
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Depositing User: VUIR
Date Deposited: 07 Jun 2012 00:51
Last Modified: 07 Jun 2012 00:51
URI: http://vuir.vu.edu.au/id/eprint/8534
DOI: https://doi.org/10.1111/j.1601-5215.2009.00416.x
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Citations in Scopus: 13 - View on Scopus

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