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Human DNAJ in cancer and stem cells

Sterrenberg, Jason and Blatch, Gregory L and Edkins, Adrienne L (2011) Human DNAJ in cancer and stem cells. Cancer Letters, 312 (2). pp. 129-142. ISSN 0304-3835

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Abstract

Molecular chaperones are the guardians of protein homeostasis in the cell. DNAJ could be regarded as potential "drug targets that chaperone other drug targets". The activities of the DNAJ proteins may mean that these proteins could be more specific and selective drug targets than HSP70 and HSP90.

Item Type: Article
Uncontrolled Keywords: ResPubID23324, Molecular chaperones, protein homeostasis, drug targets, HSP70, HSP90, stem cells, cancer, DNAJ, human DNAJ
Subjects: Faculty/School/Research Centre/Department > School of Biomedical and Health Sciences
FOR Classification > 0601 Biochemistry and Cell Biology
SEO Classification > 970111 Expanding Knowledge in the Medical and Health Sciences
Related URLs:
Depositing User: VUIR
Date Deposited: 09 Aug 2012 06:05
Last Modified: 09 Aug 2012 06:05
URI: http://vuir.vu.edu.au/id/eprint/9022
DOI: 10.1016/j.canlet.2011.08.019
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Citations in Scopus: 16 - View on Scopus

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