Research Repository

Effect of Exercise Training on Insulin Sensitivity, Mitochondria and Computed Tomography Muscle Attenuation in Overweight Women With and Without Polycystic Ovary Syndrome

Hutchison, Samantha K and Teede, Helena J and Rachon, Dominik and Harrison, Cheryce L and Strauss, Boyd J and Stepto, Nigel (2012) Effect of Exercise Training on Insulin Sensitivity, Mitochondria and Computed Tomography Muscle Attenuation in Overweight Women With and Without Polycystic Ovary Syndrome. Diabetologia, 55 (5). pp. 1424-1434. ISSN 0012-186X (print), 1432-0428 (online)

Full text for this resource is not available from the Research Repository.

Abstract

Polycystic ovary syndrome (PCOS) is an insulin resistant (IR) state. Increased skeletal muscle lipid content and impaired mitochondrial biogenesis have been implicated in the pathogenesis of IR. We investigated whether differences in these variables explain the IR of women affected by PCOS and whether improvements in IR with exercise are reflected by changes in these variables.

Item Type: Article
Uncontrolled Keywords: ResPubID23449, ResPubID25389, polycystic ovary syndrome, overweight women, body mass index, BMI, obesity, type 2 diabetes, muscles
Subjects: Faculty/School/Research Centre/Department > Institute of Sport, Exercise and Active Living (ISEAL)
FOR Classification > 1106 Human Movement and Sports Science
SEO Classification > 970111 Expanding Knowledge in the Medical and Health Sciences
Funders: http://purl.org/au-research/grants/nhmrc/606553
Depositing User: VUIR
Date Deposited: 14 Aug 2012 01:30
Last Modified: 17 Feb 2015 00:37
URI: http://vuir.vu.edu.au/id/eprint/9071
DOI: 10.1007/s00125-011-2442-8
ePrint Statistics: View download statistics for this item
Citations in Scopus: 6 - View on Scopus

Repository staff only

View Item View Item

Search Google Scholar