Skeletal muscle mitochondrial capacity and metabolism in lung transplant patients and resistance trained subjects

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Wang, Xiao Nan (2000) Skeletal muscle mitochondrial capacity and metabolism in lung transplant patients and resistance trained subjects. PhD thesis, Victoria University of Technology.

Abstract

Lung transplant (LTx) recipients have poor exercise tolerance, which persists in spite of the restoration of near normal lung function. This suggests that the exercise limitation is related to defects in skeletal muscle. Firstly, mitochondrial function and metabolism in resting skeletal muscle were examined for 7 LTx recipients, 3-24 months post operation. Secondly, exercise performance for patients with lung transplantation was investigated. Resistance training is an effective exercise mode for improving muscle bulk and strength in sports and medical rehabilitation. Recently, resistance training has become a popular exercise mode to improve muscular function and enhance exercise performance in patients with cardiopulmonary diseases. In a further study sixteen male volunteers participated in a study on the effects of resistance training on mitochondrial oxidative capacity in skeletal muscle.

Item type Thesis (PhD thesis)
URI https://vuir.vu.edu.au/id/eprint/15725
Subjects Historical > FOR Classification > 1116 Medical Physiology
Historical > FOR Classification > 1106 Human Movement and Sports Science
Historical > Faculty/School/Research Centre/Department > School of Biomedical and Health Sciences
Keywords Musculoskeletal system, Metabolism, Mitochondria, Isometric exercise, Lungs, Transplant patients
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