Forearm Vasoreactivity in Type I Diabetic Subjects

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Allen, Jason, Welsch, Michael A, Aucoin, Nikki, Wood, Robert, Lee, Matt and LeBlanc, Kim Edward (2001) Forearm Vasoreactivity in Type I Diabetic Subjects. Applied Physiology, Nutrition, and Metabolism, 26 (1). pp. 34-43. ISSN 1715-5312 (print) 1715-5320 (online)


This study compared forearm vasoreactivity in 15 Type 1 diabetic subjects with 15 healthy controls. The groups were matched for age, exercise capacity, and the absence of other cardiovascular risk factors. Vasoreactivity was measured using strain gauge plethysmography, at rest, after arterial occlusion (OCC), and following OCC coupled with handgrip exercise (ROCC). Forearm blood flows were significantly elevated between conditions 2.58 ± 0.37 ml/100mltissue at rest to 26.80 ± 6.56 after OCC and 32.80 ± 8.26ml/100mltissue following ROCC in Type 1 diabetic subjects. There were no differences in forearm blood flow between groups for any of the conditions. These data indicate the degree of forearm blood flow is directly related to the intensity of the vasodilatory stimulus. However, our study did not reveal evidence of impaired vasodilatory capacity in Type 1 diabetic subjects compared to controls in the absence of other risk factors.

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Item type Article
DOI 10.1139/h01-003
Official URL
Subjects Historical > FOR Classification > 1106 Human Movement and Sports Science
Current > Division/Research > College of Sports and Exercise Science
Keywords IDDM, vascular function, exercise, fitness, reactive hyperemia
Citations in Scopus 8 - View on Scopus
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