The role of nitrates in skeletal muscle metabolism during contraction

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Betteridge, Scott Sheng-Yi (2016) The role of nitrates in skeletal muscle metabolism during contraction. PhD thesis, Victoria University.


Inorganic nitrate (NO3-) is a chemical compound found naturally in some foods, mainly green leafy vegetables. Traditionally this anion was considered inert in the human body, but recently the consumption of dietary NO3- has been shown to result in a number of positive physiological effects. These effects include protection against ischaemic reperfusion injury and improvements in glucose regulation in diabetic animal models. Some studies have also shown a reduction in blood pressure and a decrease in oxygen consumption (VO2) for a given sub-maximal exercise workload, i.e. an increase in exercise efficiency after both acute, and chronic NO3- ingestion.

Item type Thesis (PhD thesis)
Subjects Historical > FOR Classification > 1101 Medical Biochemistry and Metabolomics
Historical > FOR Classification > 1106 Human Movement and Sports Science
Historical > Faculty/School/Research Centre/Department > Institute of Sport, Exercise and Active Living (ISEAL)
Current > Division/Research > College of Health and Biomedicine
Keywords muscles, contraction, exercise efficiency, nitric oxide, nitrite, mice, humans, glucose uptake
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