Influence of the MCT1 rs1049434 on Indirect Muscle Disorders/Injuries in Elite Football Players

Massidda, M, Eynon, Nir ORCID: 0000-0003-4046-8276, Bachis, V, Corrias, L, Culigioni, C, Piras, F, Cugia, P, Scorcu, M and Calò, CM (2015) Influence of the MCT1 rs1049434 on Indirect Muscle Disorders/Injuries in Elite Football Players. Sports Medicine - Open, 1 (1). ISSN 2199-1170


The aim of this study was to investigate the association between MCT1 rs1049434 polymorphism and indirect muscle injuries in elite football players. One hundred and seventy-three male elite Italian football players (age = 19.2 ± 5.3 years) were recruited from a first-league football club participating at the Official National Italian Football Championship (Serie A, Primavera, Allievi, Giovanissimi). The cohort was genotyped for the MCT1 rs1049434 polymorphism, and muscle injuries data were collected during the period of 2009-2014 (five football seasons).Genomic DNA was extracted using a buccal swab, and genotyping was performed using PCR method. Structural-mechanical injuries and functional muscle disorder were included in the acute indirect muscle injury group.Participants with the MCT1 AA (AA = 1.57 ± 3.07, n = 69) genotype exhibit significantly higher injury incidents compared to participants with the TT genotype (TT = 0.09 ± 0.25, n = 22, P = 0.04).The MCT1 rs1049434 polymorphism is associated with the incidence of muscle injuries in elite football players. We anticipate that the knowledge of athletes' genetic predisposition to sports-related injuries might aid in individualizing training programs.

Dimensions Badge

Altmetric Badge

Item type Article
DOI 10.1186/s40798-015-0033-9
Official URL
Subjects Historical > FOR Classification > 1106 Human Movement and Sports Science
Historical > Faculty/School/Research Centre/Department > Institute of Sport, Exercise and Active Living (ISEAL)
Keywords elite athletes; football; genetic association; lactate; muscle injuries; monocarboxylate transporter-1
Citations in Scopus 27 - View on Scopus
Download/View statistics View download statistics for this item

Search Google Scholar

Repository staff login