A Syntenic Cross Species Aneuploidy Genetic Screen Links RCAN1 Expression to β-Cell Mitochondrial Dysfunction in Type 2 Diabetes

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Peiris, Heshan, Duffield, Michael D, Fadista, Joao, Jessup, Claire F, Kashmir, Vinder, Genders, Amanda ORCID: 0000-0001-7535-4071, McGee, Sean L, Martin, Alyce M, Saiedi, Madiha, Morton, Nicholas, Carter, Roderick, Cousin, Michael A, Kokotos, Alexandros C, Oskolkov, Nikolay, Volkov, Petr, Hough, Tertius, Fisher, Elizabeth M. C, Tybulewicz, Victor L. J, Busciglio, Jorge, Coskun, Pinar E, Becker, Ann, Belichenko, Pavel V, Mobley, William C, Ryan, Michael T, Chan, Jeng Yie, Laybutt, D. Ross, Coates, P. Toby, Yang, Sijun, Ling, Charlotte, Groop, Leif, Pritchard, Melanie A and Keating, Damien J (2016) A Syntenic Cross Species Aneuploidy Genetic Screen Links RCAN1 Expression to β-Cell Mitochondrial Dysfunction in Type 2 Diabetes. PLoS Genetics, 12 (5). ISSN 1553-7390

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Item type Article
URI https://vuir.vu.edu.au/id/eprint/33259
DOI 10.1371/journal.pgen.1006033
Official URL http://journals.plos.org/plosgenetics/article?id=1...
Subjects Historical > FOR Classification > 0604 Genetics
Historical > FOR Classification > 1116 Medical Physiology
Historical > Faculty/School/Research Centre/Department > Institute of Sport, Exercise and Active Living (ISEAL)
Keywords insulin secretion; mouse models; gene expression; glucose; RCAN1; DNA methylation; T2D
Citations in Scopus 34 - View on Scopus
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