Current and emerging biomarkers of frailty in the elderly

Al Saedi, Ahmed ORCID: 0000-0002-2479-5317, Feehan, Jack ORCID: 0000-0002-9627-1299, Phu, Steven ORCID: 0000-0003-0305-9940 and Duque, Gustavo ORCID: 0000-0001-8126-0637 (2019) Current and emerging biomarkers of frailty in the elderly. Clinical Interventions in Aging, 14. pp. 389-398. ISSN 1176-9092


The term “frailty” is used to describe a subset of older adults who appear weaker and more vulnerable than their age-matched counterparts, despite having similar comorbidities, demography, sex, and age. The diagnosis of frailty is usually clinical and based on specific criteria, which are sometimes inconsistent. Therefore, there is an increasing need to identify and validate robust biomarkers for this condition. In this review, we summarize current evidence on the validity and practicality of the most commonly used biomarkers for frailty, while also comparing them with new upcoming strategies to identify this condition.

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Item type Article
DOI 10.2147/CIA.S168687
Official URL
Subjects Current > FOR (2020) Classification > 3202 Clinical sciences
Current > Division/Research > Institute for Health and Sport
Keywords frailty, biomarkers, COP cells, mesenchymal stem cells, disability, elderly
Citations in Scopus 92 - View on Scopus
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