Pathogenic mutations within the hydrophobic domain of the prion protein lead to the formation of protease-sensitive prion species with increased lethality
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Coleman, Bradley M, Harrison, Christopher F, Guo, Belinda B, Masters, Colin L ORCID: 0000-0003-3072-7940, Barnham, Kevin J ORCID: 0000-0003-1164-9465, Lawson, Victoria A ORCID: 0000-0002-7362-7176 and Hill, Andrew F ORCID: 0000-0001-5581-2354 (2014) Pathogenic mutations within the hydrophobic domain of the prion protein lead to the formation of protease-sensitive prion species with increased lethality. Journal of Virology, 88 (5). pp. 2690-2703. ISSN 0022-538X
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Item type | Article |
URI | https://vuir.vu.edu.au/id/eprint/45724 |
DOI | 10.1128/JVI.02720-13 |
Official URL | https://journals.asm.org/doi/10.1128/JVI.02720-13 |
Subjects | Current > FOR (2020) Classification > 3107 Microbiology Current > Division/Research > Chancellery |
Keywords | prion disease, prion protein, PrP, neurodegenerative disease |
Citations in Scopus | 17 - View on Scopus |
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