Effects of Beta-Alanine on Muscle Carnosine and Exercise Performance: A Review of the Current Literature

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Culbertson, Julie Y, Krieder, Richard B, Greenwood, Mike and Cooke, Matthew (2010) Effects of Beta-Alanine on Muscle Carnosine and Exercise Performance: A Review of the Current Literature. Nutrients, 2 (1). pp. 75-98. ISSN 2072-6643

Abstract

Muscle carnosine has been reported to serve as a physiological buffer, possess antioxidant properties, influence enzyme regulation, and affect sarcoplasmic reticulum calcium regulation.Beta-alanine (β-ALA) is a non-essential amino acid. β-ALA supplementation (e.g., 2–6 grams/day) has been shown to increase carnosine concentrations in skeletal muscle by 20–80%.Several studies have reported that β-ALA supplementation can increase high-intensity intermittent exercise performance and/or training adaptations. Although the specific mechanism remains to be determined, the ergogenicity of β-ALA has been most commonly attributed to an increased muscle buffering capacity.More recently, researchers have investigated the effects of co-ingesting β-ALA with creatine monohydrate to determine whether there may be synergistic and/or additive benefits. This paper overviews the theoretical rationale and potential ergogenic value of β-ALA supplementation with or without creatine as well as provides future research recommendations.

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Item type Article
URI https://vuir.vu.edu.au/id/eprint/7538
DOI https://doi.org/10.3390/nu2010075
Official URL http://www.mdpi.com/2072-6643/2/1/75/
Subjects Historical > Faculty/School/Research Centre/Department > School of Biomedical and Health Sciences
Historical > FOR Classification > 1106 Human Movement and Sports Science
Historical > FOR Classification > 1111 Nutrition and Dietetics
Keywords ResPubID21801. creatine monohydrate, anaerobic capacity, muscular fatigue, ergogenic aids, beta-alanine, muscle carnosine, exercise performance
Citations in Scopus 77 - View on Scopus
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