Osteosarcoma treatment: state of the art

Full text for this resource is not available from the Research Repository.

Ta, Hang T, Dass, Crispin R, Choong, Peter F. M and Dunstan, David E (2009) Osteosarcoma treatment: state of the art. Cancer and Metastasis Reviews, 28 (1-2). pp. 247-263. ISSN 0167-7659


Osteosarcoma (OS) is a class of cancer originating from bone, mainly afflicting children or young adults. It is the second highest cause of cancer-related death in these age groups, mainly due to development of often fatal metastasis, usually in the lungs. Survival for these patients is poor despite the aggressive use of surgery, chemotherapy, and/or radiotherapy. Thus, new effective drugs and other forms of therapy are needed. This article reviews the biology and the state of the art management of OS. New experimental drugs and potential therapies targeting molecular pathways of OS are also discussed.

Dimensions Badge

Altmetric Badge

Item type Article
URI https://vuir.vu.edu.au/id/eprint/7584
DOI 10.1007/s10555-009-9186-7
Official URL http://dx.doi.org/10.1007/s10555-009-9186-7
Subjects Historical > Faculty/School/Research Centre/Department > School of Biomedical and Health Sciences
Historical > FOR Classification > 1112 Oncology and Carcinogenesis
Historical > SEO Classification > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions)
Keywords ResPubID21881. osteosarcoma, tumours, bone cancer, chemotherapy, radiotherapy, cancer therapy lung metastasis
Citations in Scopus 278 - View on Scopus
Download/View statistics View download statistics for this item

Search Google Scholar

Repository staff login