The impact of intensified exercise training on insulin resistance and fitness in overweight and obese women with and without polycystic ovary syndrome

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Harrison, Cheryce L, Stepto, Nigel, Hutchison, Samantha K and Teede, Helena J (2012) The impact of intensified exercise training on insulin resistance and fitness in overweight and obese women with and without polycystic ovary syndrome. Clinical Endocrinology, 76 (3). pp. 351-357. ISSN 0300-0664 (print) 153102267 (online)

Abstract

This exercise intervention study was undertaken to evaluate mechanisms of insulin resistance (IR) in overweight and obese women with and without polycystic ovary syndrome (PCOS) and explore relationships between IR, fitness and body mass index (BMI) at baseline and following exercise intervention. While intensified exercise improves IR in PCOS women, a higher IR persisted following exercise in PCOS women, and a clear relationship between improved IR and improved fitness was not found. Therefore, other mechanisms of, and therapies for, IR must be explored in PCOS as IR remains higher than observed in non-PCOS controls.

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Item type Article
URI https://vuir.vu.edu.au/id/eprint/9070
DOI https://doi.org/10.1111/j.1365-2265.2011.04160.x
Official URL http://dx.doi.org/10.1111/j.1365-2265.2011.04160.x
Subjects Historical > Faculty/School/Research Centre/Department > Institute of Sport, Exercise and Active Living (ISEAL)
Historical > FOR Classification > 1106 Human Movement and Sports Science
Historical > SEO Classification > 970111 Expanding Knowledge in the Medical and Health Sciences
Keywords ResPubID23447, ResPubID25417, polycystic ovary syndrome, insulin resistance, overweight women, body mass index, BMI
Citations in Scopus 55 - View on Scopus
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