Repeated sprints alter signaling related to mitochondrial biogenesis in humans

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Serpiello, Fabio ORCID: 0000-0001-8919-3053, McKenna, Michael ORCID: 0000-0001-9998-0093, Bishop, David ORCID: 0000-0002-6956-9188, Aughey, Robert ORCID: 0000-0002-0285-8516, Caldow, Marissa K, Cameron-Smith, David and Stepto, Nigel ORCID: 0000-0002-0875-6836 (2011) Repeated sprints alter signaling related to mitochondrial biogenesis in humans. Medicine and Science in Sports and Exercise, 44 (5). pp. 827-834. ISSN 0195-9131 (print) 1530-0315 (online)


Physical exercise is used, both in acute and in chronic form, as a method to investigate the mechanisms of mitochondrial adaptations in human skeletal muscle. This study shows for the first time the effects of acute and chronic repeated sprint exercise (RSE), with short maximal sprints and brief recovery, on the molecular events associated with mitochondrial biogenesis signaling. Both acute and chronic RSE, despite only 60 s and 12 min of exercise, respectively, altered the molecular associated with mitochondrial adaptations

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Item type Article
DOI 10.1249/MSS.0b013e318240067e
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Subjects Historical > FOR Classification > 1106 Human Movement and Sports Science
Historical > Faculty/School/Research Centre/Department > School of Sport and Exercise Science
Historical > SEO Classification > 970111 Expanding Knowledge in the Medical and Health Sciences
Historical > Faculty/School/Research Centre/Department > Institute of Sport, Exercise and Active Living (ISEAL)
Keywords ResPubID23483, ResPubID25400, repeated sprint exercise (RSE), high-intensity intermittent training, protein signalling, mitochondrial biogenesis
Citations in Scopus 35 - View on Scopus
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