The major focus of this thesis was to examine the effect of sprint training on skeletal muscle purine nucleotide (PnN) metabolism. Specifically, this thesis studied the effects of sprint training on skeletal muscle PnN and metabolites of
purine catabolism at rest, during a 30 s "all out" cycle bout and after 3 min of recovery. Furthermore, the accumulation of purine degradation prcducts in the plasma (ammonia, hypoxanthine) during exercise, and in recovery from a 30 s "all out" sprint was also examined. Finally, this thesis studied the influence of sprint training on performance variables pertinent to sprint exercise.