Limited information is available on the direct role of vitamin D metabolites (calcidiol and calcitriol) in skin carcinogenesis. For most individuals, skin cancer can be readily managed with surgery; however, some patients may face life-threatening neoplasia. Sun exposure, specifically ultraviolet radiation, is a causative agent for development of skin cancer, though, somewhat ironically, sunlight through the endogenous production of vitamin D may have a protective effect against some skin cancers.