OA - HD 24/5/17. -- Info for Publisher: Open Access: This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. -- Full-text added 30.5.17-MMM Grant information added, LL 8/12/20