predictive preventive personalised medicine; 3PM; PPPM; oncology; tumour; plant natural substances; phytochemicals; antimutagenic effects; genomic instability; genotoxicity; prebiotic; probiotic; anti-inflammatory; antioxidant; antibacterial; antifungal; anticancer; beneficiary effects; genoprotection; chemoprevention;  superoxide dismutase; hydrogen peroxide; glutathione; thioredoxin; glutaredoxins; ROS; scavanger; preclinical and clinical study; exogenous and endogenous agents; oxidative stress; biomarkers; therapeutic potential; diet; nanoparticles; nanotechnology; detoxification; breast cancer; colon cancer