In the traditional medicine of Europe, raw potatoes are used for gastrointestinal disorders, and topical potato
preparations as a hot pack for pain or for softening furuncles. The aim of this study was to review the literature
and summarize the data on the medicinal use of potato-derived products. Several databases and other sources
were searched to identify clinical trials investigating potato-derived preparations. The trials were analysed for
quality. Five trials were identified; two open uncontrolled studies, two open controlled studies and one doubleblind
study. These results stimulate further investigation of oral potato juice concentrate in patients with
dyspeptic complaints, of potato proteinase inhibitor II for weight reduction, and of topical potato proteins for
preventing protease-induced perianal dermatitis. We recommend that future studies have a confirmatory
design.