Mobile computing can potentially change the way medical, health and information services are delivered. Much of the focus has been on mobile telephone use particularly from a commercial and marketing perspective. It is often assumed that ‘mobile’ means using a mobile telephone. The growth in mobile devices usage in hospitals, is contributing to better health and medical services delivery. This paper describes two hospital based case studies involving different mobile devices. We argue that understanding the mobile domain in hospitals requires an understanding of both the context and the user, we propose a definition of the mobile hospital work domain.