Cardiovascular disease which is mainly caused by atherosclerosis has the highest mortality rate in Australia. The Chinese therapeutic food, hawthorn fruit and Chinese kiwifruit, is recognized as both food and herbal medicine by the Chinese Ministry of Health. Previous studies have shown favorable effects of both on the treatment of dyslipidemia and atherosclerosis. This clinical study suggests that the intake of hawthorn fruit and Chinese kiwifruit supplement may increase the serum levels of HDL-c and decrease the ratios of TC/HDL-c and LDL-c/HDL-c, and therefore may reduce the risk of cardiovascular disease.