Article

Su, Huaqi, Rustam, Yepy H, Masters, Colin L ORCID: 0000-0003-3072-7940, Makalic, Enes, McLean, Catirona ORCID: 0000-0002-9259-8411, Hill, Andrew F ORCID: 0000-0001-5581-2354, Barnham, Kevin J ORCID: 0000-0003-1164-9465, Reid, Gavin E and Vella, Laura J ORCID: 0000-0002-1869-6291 (2021) Characterization of brain-derived extracellular vesicle lipids in Alzheimer's disease. Journal of Extracellular Vesicles, 10 (7). ISSN 2001-3078

Cheng, Lesley ORCID: 0000-0002-8075-6144, Vella, Laura, Barnham, Kevin J ORCID: 0000-0003-1164-9465, McLean, Catirona ORCID: 0000-0002-9259-8411, Masters, Colin L ORCID: 0000-0003-3072-7940 and Hill, Andrew F ORCID: 0000-0001-5581-2354 (2020) Small RNA fingerprinting of Alzheimer’s disease frontal cortex extracellular vesiclesand their comparison with peripheral extracellular vesicles. Journal of Extracellular Vesicles, 9 (1). ISSN 2001-3078

Vella, Laura J ORCID: 0000-0002-1869-6291, Scicluna, Benjamin J ORCID: 0000-0001-6828-9910, Cheng, Lesley ORCID: 0000-0002-8075-6144, Bawden, Emma G, Masters, Colin L ORCID: 0000-0003-3072-7940, Ang, Ching-Seng, Willamson, Nicholas, McLean, Catirona ORCID: 0000-0002-9259-8411, Barnham, Kevin J ORCID: 0000-0003-1164-9465 and Hill, Andrew F ORCID: 0000-0001-5581-2354 (2017) A rigorous method to enrich for exosomes from brain tissue. Journal of Extracellular Vesicles, 6 (1). ISSN 2001-3078

Cheng, Lesley ORCID: 0000-0002-8075-6144, Quek, Camelia YJ, Hung, Lin W, Sharples, Robyn A, Sherratt, Nicki A, Barnham, Kevin J ORCID: 0000-0003-1164-9465 and Hill, Andrew F ORCID: 0000-0001-5581-2354 (2016) Gene dysregulation is restored in the Parkinson's disease MPTP neurotoxic mice model upon treatment of the therapeutic drug CuII (atsm). Scientific Reports, 6. ISSN 2045-2322

Johanssen, Timothy ORCID: 0000-0001-6757-586X, Suphantarida, Nuttawat, Donnelly, Paul S, Liu, Xiang M, Petrou, Steven ORCID: 0000-0002-4960-6375, Hill, Andrew F ORCID: 0000-0001-5581-2354 and Barnham, Kevin J ORCID: 0000-0003-1164-9465 (2015) PBT2 inhibits glutamate-induced excitotoxicity in neurons through metal-mediated preconditioning. Neurobiology of Disease, 81. pp. 176-185. ISSN 0969-9961

Johanssen, Vanessa A, Johanssen, Timothy ORCID: 0000-0001-6757-586X, Masters, Colin L ORCID: 0000-0003-3072-7940, Hill, Andrew F ORCID: 0000-0001-5581-2354, Barnham, Kevin J ORCID: 0000-0003-1164-9465 and Collins, Steven J (2014) C-terminal peptides modelling constitutive PrPC processing demonstrate ameliorated toxicity predisposition consequent to α-cleavage. Biochemical Journal, 459 (1). pp. 103-115. ISSN 0264-6021

Coleman, Bradley M, Harrison, Christopher F, Guo, Belinda B, Masters, Colin L ORCID: 0000-0003-3072-7940, Barnham, Kevin J ORCID: 0000-0003-1164-9465, Lawson, Victoria A ORCID: 0000-0002-7362-7176 and Hill, Andrew F ORCID: 0000-0001-5581-2354 (2014) Pathogenic mutations within the hydrophobic domain of the prion protein lead to the formation of protease-sensitive prion species with increased lethality. Journal of Virology, 88 (5). pp. 2690-2703. ISSN 0022-538X

Hung, Lin W, Villemagne, Victor L, Cheng, Lesley, Sherratt, Nicki A, Ayton, Scott, White, Anthony R ORCID: 0000-0003-1802-9891, Crouch, Peter J, Lim, SinChun, Leong, Su Ling, Wilkins, Simon, George, Jessica, Roberts, Blaine R, Pham, Chi LL, Liu, Xiang, Chiu, Francis CK, Shackleford, David M, Powell, Andrew K, Masters, Colin L ORCID: 0000-0003-3072-7940, Bush, Ashley I ORCID: 0000-0001-8259-9069, O'Keefe, Graeme, Culvenor, Janetta G, Cappai, Roberto ORCID: 0000-0002-9505-8496, Cherny, Robert A, Donnelly, Paul S, Hill, Andrew F ORCID: 0000-0001-5581-2354, Finkelstein, David I and Barnham, Kevin J ORCID: 0000-0003-1164-9465 (2012) The hypoxia imaging agent Cu ii(atsm) is neuroprotective and improves motor and cognitive functions in multiple animal models of Parkinson's disease. Journal of Experimental Medicine, 209 (4). pp. 837-854. ISSN 0022-1007

Johanssen, Vanessa A, Barnham, Kevin J ORCID: 0000-0003-1164-9465, Masters, Colin L ORCID: 0000-0003-3072-7940, Hill, Andrew F ORCID: 0000-0001-5581-2354 and Collins, Steven J (2012) Generating recombinant C-terminal prion protein fragments of exact native sequence. Neurochemistry International, 60 (3). pp. 318-326. ISSN 0197-0186

Karas, John A, Boland, Martin P, Haigh, Cathryn L, Johanssen, Vanessa A, Hill, Andrew F ORCID: 0000-0001-5581-2354, Barnham, Kevin J ORCID: 0000-0003-1164-9465, Collins, Steven J and Scanlon, Denis (2011) Microwave synthesis of prion protein fragments up to 111 amino acids in length generates biologically active peptides. International Journal of Peptide Research and Therapeutics, 18. pp. 21-29. ISSN 1573-3149

Boland, Martin P, Hatty, Claire R, Separovic, Frances, Hill, Andrew F ORCID: 0000-0001-5581-2354, Tew, Deborah J, Barnham, Kevin J ORCID: 0000-0003-1164-9465, Haigh, Cathryn L, James, Michael, Masters, Colin L ORCID: 0000-0003-3072-7940 and Collins, Steven J (2010) Anionic phospholipid interactions of the prion protein N terminus are minimally perturbing and not driven solely by the octapeptide repeat domain. Journal of Biological Chemistry, 285 (42). pp. 32282-32292. ISSN 0021-9258

Harrison, Christopher F, Lawson, Victoria A ORCID: 0000-0002-7362-7176, Coleman, Bradley M, Kim, Y-S, Masters, Colin L ORCID: 0000-0003-3072-7940, Cappai, Roberto ORCID: 0000-0002-9505-8496, Barnham, Kevin J ORCID: 0000-0003-1164-9465 and Hill, Andrew F ORCID: 0000-0001-5581-2354 (2010) Conservation of a glycine-rich region in the prion protein is required for uptake of prion infectivity. Journal of Biological Chemistry, 285 (26). pp. 20213-20223. ISSN 0021-9258

Leong, Su Ling, Pham, Chi LL, Galatis, Denise, Fodero-Tavoletti, Michelle T, Perez, Keyla, Hill, Andrew F ORCID: 0000-0001-5581-2354, Masters, Colin L ORCID: 0000-0003-3072-7940, Ali, Feda E, Barnham, Kevin J ORCID: 0000-0003-1164-9465 and Cappai, Roberto ORCID: 0000-0002-9505-8496 (2009) Formation of dopamine-mediated α-synuclein-soluble oligomers requires methionine oxidation. Free Radical Biology and Medicine, 46 (10). pp. 1328-1337. ISSN 0891-5849

Pham, Chi LL, Leong, Su Ling, Ali, Feda E, Kenche, Vijaya B ORCID: 0000-0003-4424-4886, Hill, Andrew F ORCID: 0000-0001-5581-2354, Gras, Sally L ORCID: 0000-0002-4660-1245, Barnham, Kevin J ORCID: 0000-0003-1164-9465 and Cappai, Roberto ORCID: 0000-0002-9505-8496 (2009) Dopamine and the dopamine oxidation product 5,6-dihydroxylindole promote distinct on-pathway and off-pathway aggregation of α-synuclein in a pH-dependent manner. Journal of Molecular Biology, 387 (3). pp. 771-785. ISSN 0022-2836

Naylor, Ryan, Hill, Andrew F ORCID: 0000-0001-5581-2354 and Barnham, Kevin J ORCID: 0000-0003-1164-9465 (2008) Is covalently crosslinked Aβ responsible for synaptotoxicity in Alzheimer's disease? Current Alzheimer Research, 5 (6). pp. 533-539. ISSN 1567-2050

Sharples, Robyn A, Vella, Laura, Nisbet, Rebecca M, Naylor, Ryan, Perez, Keyla, Barnham, Kevin J, Masters, Colin L ORCID: 0000-0003-3072-7940 and Hill, Andrew F ORCID: 0000-0001-5581-2354 (2008) Inhibition of γ-secretase causes increased secretion of amyloid precursor protein C-terminal fragments in association with exosomes. FASEB Journal, 22 (5). pp. 1469-1478. ISSN 0892-6638

Donnelly, Paul S, Caragounis, Aphrodite, Du, Tai, Laughton, Katrina M, Volitakis, Irene, Cherny, Robert A, Sharples, Robyn A, Hill, Andrew F ORCID: 0000-0001-5581-2354, Li, Qiao-Xin, Masters, Colin L ORCID: 0000-0003-3072-7940, Barnham, Kevin J and White, Anthony R ORCID: 0000-0003-1802-9891 (2008) Selective intracellular release of copper and zinc ions from bis(thiosemicarbazonato) complexes reduces levels of Alzheimer disease amyloid-β peptide. Journal of Biological Chemistry, 283 (8). pp. 4568-4577. ISSN 0021-9258

Price, Katherine A, Filiz, Gulay, Caragounis, Aphrodite, Du, Tai, Laughton, Katrina M, Masters, Colin L ORCID: 0000-0003-3072-7940, Sharples, Robyn A, Hill, Andrew F ORCID: 0000-0001-5581-2354, Li, Qiao-Xin, Donnelly, Paul S, Barnham, Kevin J ORCID: 0000-0003-1164-9465, Crouch, Peter J and White, Anthony R ORCID: 0000-0003-1802-9891 (2008) Activation of epidermal growth factor receptor by metal-ligand complexes decreases levels of extracellular amyloid beta peptide. International Journal of Biochemistry and Cell Biology, 40 (9). pp. 1901-1917. ISSN 1357-2725

Smith, David P, Tew, Deborah J, Hill, Andrew F ORCID: 0000-0001-5581-2354, Bottomley, Stephen P, Masters, Colin L ORCID: 0000-0003-3072-7940, Barnham, Kevin J ORCID: 0000-0003-1164-9465 and Cappai, Roberto ORCID: 0000-0002-9505-8496 (2008) Formation of a high affinity lipid-binding intermediate during the early aggregation phase of α-synuclein. Biochemistry, 47 (5). pp. 1425-1434. ISSN 0006-2960

Naylor, Ryan, Hill, Andrew F ORCID: 0000-0001-5581-2354 and Barnham, Kevin J (2007) Neurotoxicity in Alzheimer's disease: is covalently crosslinked Aβ responsible? European Biophysics Journal, 37. pp. 265-268. ISSN 0175-7571

Caragounis, Aphrodite, Du, Tai, Filiz, Gulay, Laughton, Katrina M, Volitakis, Irene, Sharples, Robyn A, Cherny, Robert A, Masters, Colin L ORCID: 0000-0003-3072-7940, Drew, Simon C, Hill, Andrew F ORCID: 0000-0001-5581-2354, Li, Qiao-Xin, Crouch, Peter J, Barnham, Kevin J ORCID: 0000-0003-1164-9465 and White, Anthony R ORCID: 0000-0003-1802-9891 (2007) Differential modulation of Alzheimer's disease amyloid β-peptide accumulation by diverse classes of metal ligands. Biochemical Journal, 407 (3). pp. 435-450. ISSN 0264-6021

Harrison, Christopher F, Barnham, Kevin J and Hill, Andrew F ORCID: 0000-0001-5581-2354 (2007) Neurotoxic species in prion disease: a role for PrP isoforms? Journal of Neurochemistry, 103 (5). pp. 1709-1720. ISSN 0022-3042

Barnham, Kevin J, Cappai, Roberto ORCID: 0000-0002-9505-8496, Beyreuther, Konrad, Masters, Colin L ORCID: 0000-0003-3072-7940 and Hill, Andrew F ORCID: 0000-0001-5581-2354 (2006) Delineating common molecular mechanisms in Alzheimer's and prion diseases. Trends in Biochemical Sciences, 31 (8). pp. 465-472. ISSN 0968-0004

White, Anthony R ORCID: 0000-0003-1802-9891, Du, Tai, Laughton, Katrina M, Volitakis, Irene, Sharples, Robyn A, Xilinas, Michael E, Hoke, David E, Holsinger, RM Damian ORCID: 0000-0002-4447-0835, Evin, Genevie`ve, Cherny, Robert A, Hill, Andrew F ORCID: 0000-0001-5581-2354, Barnham, Kevin J ORCID: 0000-0003-1164-9465, Li, Qiao-Xin, Bush, Ashley I ORCID: 0000-0001-8259-9069 and Masters, Colin L ORCID: 0000-0003-3072-7940 (2006) Degradation of the Alzheimer disease amyloid β-peptide by metal-dependent up-regulation of metalloprotease activity. Journal of Biological Chemistry, 281 (26). pp. 17670-17680. ISSN 0021-9258

Cappai, Roberto ORCID: 0000-0002-9505-8496, Leek, Su-Ling, Tew, Deborah J, Williamson, Nicholas A ORCID: 0000-0002-2173-3452, Smith, David P, Galatis, Denise, Sharples, Robyn A, Curtain, Cyril C, Ali, Feda E, Cherny, Robert A, Culvenor, Janetta G, Bottomley, Stephen P, Masters, Colin L ORCID: 0000-0003-3072-7940, Barnham, Kevin J ORCID: 0000-0003-1164-9465 and Hill, Andrew F ORCID: 0000-0001-5581-2354 (2005) Dopamine promotes α-synuclein aggregation into SDS-resistant soluble oligomers via a distinct folding pathway. FASEB Journal, 19 (10). pp. 1377-1379. ISSN 0892-6638

Book

Hill, Andrew F ORCID: 0000-0001-5581-2354, Barnham, Kevin J ORCID: 0000-0003-1164-9465, Bottomley, Stephen P and Cappai, Roberto ORCID: 0000-0002-9505-8496, eds. (2011) Protein folding, misfolding, and disease: methods and protocols. Methods in Molecular Biology, 752 . Humana Totowa, NJ, USA, pp. 1-249.

Book Section

Miles, Luke A, Crespi, Gabriela AN, Han, Sen, Hill, Andrew F ORCID: 0000-0001-5581-2354 and Parker, Michael W (2011) An Escherichia coli Cell-Free System for Recombinant Protein Synthesis on a Milligram Scale. In: Protein Folding, Misfolding, and Disease: Methods and Protocols. Hill, Andrew F, Barnham, Kevin J, Bottomley, SP and Cappai, Roberto, eds. Methods in Molecular Biology, 752 . Springer, USA, pp. 17-28.