Article

Falsone, S Fabio, Meyer, N Helge, Schrank, Evelyne, Leitinger, Gerd, Pham, Chi LL, Fodero-Tavoletti, Michelle T, Holmberg, Mats, Dulle, Martin, Scicluna, Benjamin J, Gesslbauer, Bernd ORCID: https://orcid.org/0000-0003-4910-8322, Rückert, Hanna-Marie, Wagner, Gabriel E ORCID: https://orcid.org/0000-0002-5704-3955, Merle, David A, Nollen, Ellen A, Kungl, Andreas J, Hill, Andrew F ORCID: https://orcid.org/0000-0001-5581-2354, Cappai, Roberto ORCID: https://orcid.org/0000-0002-9505-8496 and Zangger, Klaus ORCID: https://orcid.org/0000-0003-1682-1594 (2012) SERF protein is a direct modifier of amyloid fiber assembly. Cell Reports, 2 (2). pp. 358-371. ISSN 2211-1247

Hung, Lin W, Villemagne, Victor L, Cheng, Lesley, Sherratt, Nicki A, Ayton, Scott, White, Anthony R ORCID: https://orcid.org/0000-0003-1802-9891, Crouch, Peter J, Lim, SinChun, Leong, Su Ling, Wilkins, Simon, George, Jessica, Roberts, Blaine R, Pham, Chi LL, Liu, Xiang, Chiu, Francis CK, Shackleford, David M, Powell, Andrew K, Masters, Colin L ORCID: https://orcid.org/0000-0003-3072-7940, Bush, Ashley I ORCID: https://orcid.org/0000-0001-8259-9069, O'Keefe, Graeme, Culvenor, Janetta G, Cappai, Roberto ORCID: https://orcid.org/0000-0002-9505-8496, Cherny, Robert A, Donnelly, Paul S, Hill, Andrew F ORCID: https://orcid.org/0000-0001-5581-2354, Finkelstein, David I and Barnham, Kevin J ORCID: https://orcid.org/0000-0003-1164-9465 (2012) The hypoxia imaging agent Cu ii(atsm) is neuroprotective and improves motor and cognitive functions in multiple animal models of Parkinson's disease. Journal of Experimental Medicine, 209 (4). pp. 837-854. ISSN 0022-1007

Dinet, Virginie, An, Na, Ciccotosto, Giuseppe D, Bruban, Julien, Maoui, Agathe, Bellingham, Shayne A ORCID: https://orcid.org/0000-0001-5657-7413, Hill, Andrew F ORCID: https://orcid.org/0000-0001-5581-2354, Andersen, Olav M, Nykjaer, Anders, Jonet, Laurent, Cappai, Roberto ORCID: https://orcid.org/0000-0002-9505-8496 and Mascarelli, Frédéric (2010) APP involvement in retinogenesis of mice. Acta Neuropathologica, 121. pp. 351-363. ISSN 0001-6322

Nisbet, Rebecca M, Harrison, Christopher F, Lawson, Victoria A ORCID: https://orcid.org/0000-0002-7362-7176, Masters, Colin L ORCID: https://orcid.org/0000-0003-3072-7940, Cappai, Roberto ORCID: https://orcid.org/0000-0002-9505-8496 and Hill, Andrew F ORCID: https://orcid.org/0000-0001-5581-2354 (2010) Residues surrounding the glycosylphosphatidylinositol anchor attachment site of PrP modulate prion infection: insight from the resistance of rabbits to prion disease. Journal of Virology, 84 (13). pp. 6678-6686. ISSN 0022-538X

Harrison, Christopher F, Lawson, Victoria A ORCID: https://orcid.org/0000-0002-7362-7176, Coleman, Bradley M, Kim, Y-S, Masters, Colin L ORCID: https://orcid.org/0000-0003-3072-7940, Cappai, Roberto ORCID: https://orcid.org/0000-0002-9505-8496, Barnham, Kevin J ORCID: https://orcid.org/0000-0003-1164-9465 and Hill, Andrew F ORCID: https://orcid.org/0000-0001-5581-2354 (2010) Conservation of a glycine-rich region in the prion protein is required for uptake of prion infectivity. Journal of Biological Chemistry, 285 (26). pp. 20213-20223. ISSN 0021-9258

Perreau, Victoria M, Orchard, Sandra, Adlard, Paul A, Bellingham, Shayne A ORCID: https://orcid.org/0000-0001-5657-7413, Cappai, Roberto ORCID: https://orcid.org/0000-0002-9505-8496, Ciccotosto, Giuseppe D, Cowie, Tiffany F, Crouch, Peter J, Duce, James A, Evin, Genevie`ve, Faux, Noel G, Hill, Andrew F ORCID: https://orcid.org/0000-0001-5581-2354, Hung, Ya Hui, James, SA, Li, Qiao-Xin, Mok, Su San, Tew, Deborah J, White, Anthony R ORCID: https://orcid.org/0000-0003-1802-9891, Bush, Ashley I ORCID: https://orcid.org/0000-0001-8259-9069, Hermjakob, Henning and Masters, Colin L ORCID: https://orcid.org/0000-0003-3072-7940 (2010) A domain level interaction network of amyloid precursor protein and Aβ of Alzheimer's disease. Proteomics, 10 (12). pp. 2377-2395. ISSN 1615-9853

Leong, Su Ling, Pham, Chi LL, Galatis, Denise, Fodero-Tavoletti, Michelle T, Perez, Keyla, Hill, Andrew F ORCID: https://orcid.org/0000-0001-5581-2354, Masters, Colin L ORCID: https://orcid.org/0000-0003-3072-7940, Ali, Feda E, Barnham, Kevin J ORCID: https://orcid.org/0000-0003-1164-9465 and Cappai, Roberto ORCID: https://orcid.org/0000-0002-9505-8496 (2009) Formation of dopamine-mediated α-synuclein-soluble oligomers requires methionine oxidation. Free Radical Biology and Medicine, 46 (10). pp. 1328-1337. ISSN 0891-5849

Pham, Chi LL, Leong, Su Ling, Ali, Feda E, Kenche, Vijaya B ORCID: https://orcid.org/0000-0003-4424-4886, Hill, Andrew F ORCID: https://orcid.org/0000-0001-5581-2354, Gras, Sally L ORCID: https://orcid.org/0000-0002-4660-1245, Barnham, Kevin J ORCID: https://orcid.org/0000-0003-1164-9465 and Cappai, Roberto ORCID: https://orcid.org/0000-0002-9505-8496 (2009) Dopamine and the dopamine oxidation product 5,6-dihydroxylindole promote distinct on-pathway and off-pathway aggregation of α-synuclein in a pH-dependent manner. Journal of Molecular Biology, 387 (3). pp. 771-785. ISSN 0022-2836

Coleman, Bradley M, Nisbet, Rebecca M ORCID: https://orcid.org/0000-0002-3751-9119, Han, Sen, Cappai, Roberto ORCID: https://orcid.org/0000-0002-9505-8496, Hatters, Danny M ORCID: https://orcid.org/0000-0002-9965-2847 and Hill, Andrew F ORCID: https://orcid.org/0000-0001-5581-2354 (2009) Conformational detection of prion protein with biarsenical labeling and FlAsH fluorescence. Biochemical and Biophysical Research Communications, 380 (3). pp. 564-568. ISSN 0006-291X

Vella, Laura J ORCID: https://orcid.org/0000-0002-1869-6291, Greenwood, Deanne LV, Cappai, Roberto ORCID: https://orcid.org/0000-0002-9505-8496, Scheerlinck, Jean-Pierre Y ORCID: https://orcid.org/0000-0002-8385-353X and Hill, Andrew F ORCID: https://orcid.org/0000-0001-5581-2354 (2008) Enrichment of prion protein in exosomes derived from ovine cerebral spinal fluid. Veterinary Immunology and Immunopathology, 124 (3-4). pp. 385-393. ISSN 0165-2427

Chan, Sharon L, Kim, Woojin Scott, Kwok, John B, Hill, Andrew F ORCID: https://orcid.org/0000-0001-5581-2354, Cappai, Roberto ORCID: https://orcid.org/0000-0002-9505-8496, Rye, Kerry-Anne and Garner, Brett (2008) ATP-binding cassette transporter A7 regulates processing of amyloid precursor protein in vitro. Journal of Neurochemistry, 106 (2). pp. 793-804. ISSN 0022-3042

Lawson, Victoria A ORCID: https://orcid.org/0000-0002-7362-7176, Vella, Laura J ORCID: https://orcid.org/0000-0002-1869-6291, Stewart, James D, Sharples, Robyn A, Klemm, Helen MJ, Machalek, Dorothy, Masters, Colin L ORCID: https://orcid.org/0000-0003-3072-7940, Cappai, Roberto ORCID: https://orcid.org/0000-0002-9505-8496, Collins, Steven J and Hill, Andrew F ORCID: https://orcid.org/0000-0001-5581-2354 (2008) Mouse-adapted sporadic human Creutzfeldt-Jakob disease prions propagate in cell culture. International Journal of Biochemistry and Cell Biology, 40 (12). pp. 2793-2801. ISSN 1357-2725

Albanese, Valeria ORCID: https://orcid.org/0000-0002-9643-7519, Lawson, Victoria A ORCID: https://orcid.org/0000-0002-7362-7176, Hill, Andrew F ORCID: https://orcid.org/0000-0001-5581-2354, Cappai, Roberto ORCID: https://orcid.org/0000-0002-9505-8496, Di Guardo, Giovanni, Staikopoulos, Vasiliki, Thacker, Michelle, Furness, John B ORCID: https://orcid.org/0000-0002-0219-3438 and Chiocchetti, Roberto ORCID: https://orcid.org/0000-0003-4448-6199 (2008) Evidence for prion protein expression in enteroglial cells of the myenteric plexus of mouse intestine. Autonomic Neuroscience: Basic and Clinical, 140 (1-2). pp. 17-23. ISSN 1566-0702

Smith, David P, Tew, Deborah J, Hill, Andrew F ORCID: https://orcid.org/0000-0001-5581-2354, Bottomley, Stephen P, Masters, Colin L ORCID: https://orcid.org/0000-0003-3072-7940, Barnham, Kevin J ORCID: https://orcid.org/0000-0003-1164-9465 and Cappai, Roberto ORCID: https://orcid.org/0000-0002-9505-8496 (2008) Formation of a high affinity lipid-binding intermediate during the early aggregation phase of α-synuclein. Biochemistry, 47 (5). pp. 1425-1434. ISSN 0006-2960

Vella, Laura, Sharples, Robyn A, Nisbet, Rebecca M, Cappai, Roberto ORCID: https://orcid.org/0000-0002-9505-8496 and Hill, Andrew F ORCID: https://orcid.org/0000-0001-5581-2354 (2007) The role of exosomes in the processing of proteins associated with neurodegenerative diseases. European Biophysics Journal, 37. pp. 323-332. ISSN 0175-7571

Vella, Laura, Sharples, Robyn A, Lawson, Victoria A ORCID: https://orcid.org/0000-0002-7362-7176, Masters, Colin L ORCID: https://orcid.org/0000-0003-3072-7940, Cappai, Roberto ORCID: https://orcid.org/0000-0002-9505-8496 and Hill, Andrew F ORCID: https://orcid.org/0000-0001-5581-2354 (2007) Packaging of prions into exosomes is associated with a novel pathway of PrP processing. Journal of Pathology, 211 (5). pp. 582-590. ISSN 0022-3417

Barnham, Kevin J, Cappai, Roberto ORCID: https://orcid.org/0000-0002-9505-8496, Beyreuther, Konrad, Masters, Colin L ORCID: https://orcid.org/0000-0003-3072-7940 and Hill, Andrew F ORCID: https://orcid.org/0000-0001-5581-2354 (2006) Delineating common molecular mechanisms in Alzheimer's and prion diseases. Trends in Biochemical Sciences, 31 (8). pp. 465-472. ISSN 0968-0004

Yuan, Fang F, Biffin, Sandra, Brazier, Marcus W, Suarez, Monica, Cappai, Roberto ORCID: https://orcid.org/0000-0002-9505-8496, Hill, Andrew F ORCID: https://orcid.org/0000-0001-5581-2354, Collins, Steven J, Sullivan, John S, Middleton, Deborah, Multhaup, Gerd, Geczy, AF and Masters, Colin L ORCID: https://orcid.org/0000-0003-3072-7940 (2005) Detection of prion epitopes on PrPc and PrPsc of transmissible spongiform encephalopathies using specific monoclonal antibodies to PrP. Immunology and Cell Biology, 83 (6). pp. 632-637. ISSN 0818-9641

Brazier, Marcus W, Lewis, Victoria A, Ciccotosto, Giuseppe D, Klug, Genevieve M, Lawson, Victoria A ORCID: https://orcid.org/0000-0002-7362-7176, Cappai, Roberto ORCID: https://orcid.org/0000-0002-9505-8496, Ironside, James W, Masters, Colin L ORCID: https://orcid.org/0000-0003-3072-7940, Hill, Andrew F ORCID: https://orcid.org/0000-0001-5581-2354, White, Anthony R ORCID: https://orcid.org/0000-0003-1802-9891 and Collins, Steven J (2005) Correlative studies support lipid peroxidation is linked to PrPres propagation as an early primary pathogenic event in prion disease. Brain Research Bulletin, 68 (5). pp. 346-354. ISSN 0361-9230

Cappai, Roberto ORCID: https://orcid.org/0000-0002-9505-8496, Leek, Su-Ling, Tew, Deborah J, Williamson, Nicholas A ORCID: https://orcid.org/0000-0002-2173-3452, Smith, David P, Galatis, Denise, Sharples, Robyn A, Curtain, Cyril C, Ali, Feda E, Cherny, Robert A, Culvenor, Janetta G, Bottomley, Stephen P, Masters, Colin L ORCID: https://orcid.org/0000-0003-3072-7940, Barnham, Kevin J ORCID: https://orcid.org/0000-0003-1164-9465 and Hill, Andrew F ORCID: https://orcid.org/0000-0001-5581-2354 (2005) Dopamine promotes α-synuclein aggregation into SDS-resistant soluble oligomers via a distinct folding pathway. FASEB Journal, 19 (10). pp. 1377-1379. ISSN 0892-6638

White, Anthony R ORCID: https://orcid.org/0000-0003-1802-9891, Guirguis, Ronald, Brazier, Marcus W, Jobling, Michael F, Hill, Andrew F ORCID: https://orcid.org/0000-0001-5581-2354, Beyreuther, Konrad, Barrow, Colin J, Masters, Colin L ORCID: https://orcid.org/0000-0003-3072-7940, Collins, Steven J and Cappai, Roberto ORCID: https://orcid.org/0000-0002-9505-8496 (2002) Sublethal concentrations of prion peptide PrP106-126 or the amyloid beta peptide of Alzheimer's disease activates expression of proapoptotic markers in primary cortical neurons. Neurobiology of Disease, 8 (2). pp. 299-316. ISSN 0969-9961

Book

Hill, Andrew F ORCID: https://orcid.org/0000-0001-5581-2354, Barnham, Kevin J ORCID: https://orcid.org/0000-0003-1164-9465, Bottomley, Stephen P and Cappai, Roberto ORCID: https://orcid.org/0000-0002-9505-8496, eds. (2011) Protein folding, misfolding, and disease: methods and protocols. Methods in Molecular Biology, 752 . Humana Totowa, NJ, USA, pp. 1-249.

Book Section

Miles, Luke A, Crespi, Gabriela AN, Han, Sen, Hill, Andrew F ORCID: https://orcid.org/0000-0001-5581-2354 and Parker, Michael W (2011) An Escherichia coli Cell-Free System for Recombinant Protein Synthesis on a Milligram Scale. In: Protein Folding, Misfolding, and Disease: Methods and Protocols. Hill, Andrew F, Barnham, Kevin J, Bottomley, SP and Cappai, Roberto, eds. Methods in Molecular Biology, 752 . Springer, USA, pp. 17-28.

Vella, Laura, Hill, Andrew F ORCID: https://orcid.org/0000-0001-5581-2354 and Cappai, Roberto ORCID: https://orcid.org/0000-0002-9505-8496 (2005) Mechanisms of prion toxicity and their relationship to prion infectivity. In: Neurodegeneration and Prion Disease. Springer, New York, USA, pp. 217-240.