Article

Falsone, S Fabio, Meyer, N Helge, Schrank, Evelyne, Leitinger, Gerd, Pham, Chi LL, Fodero-Tavoletti, Michelle T, Holmberg, Mats, Dulle, Martin, Scicluna, Benjamin J, Gesslbauer, Bernd ORCID: 0000-0003-4910-8322, Rückert, Hanna-Marie, Wagner, Gabriel E ORCID: 0000-0002-5704-3955, Merle, David A, Nollen, Ellen A, Kungl, Andreas J, Hill, Andrew F ORCID: 0000-0001-5581-2354, Cappai, Roberto ORCID: 0000-0002-9505-8496 and Zangger, Klaus ORCID: 0000-0003-1682-1594 (2012) SERF protein is a direct modifier of amyloid fiber assembly. Cell Reports, 2 (2). pp. 358-371. ISSN 2211-1247

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Dinet, Virginie, An, Na, Ciccotosto, Giuseppe D, Bruban, Julien, Maoui, Agathe, Bellingham, Shayne A ORCID: 0000-0001-5657-7413, Hill, Andrew F ORCID: 0000-0001-5581-2354, Andersen, Olav M, Nykjaer, Anders, Jonet, Laurent, Cappai, Roberto ORCID: 0000-0002-9505-8496 and Mascarelli, Frédéric (2010) APP involvement in retinogenesis of mice. Acta Neuropathologica, 121. pp. 351-363. ISSN 0001-6322

Nisbet, Rebecca M, Harrison, Christopher F, Lawson, Victoria A ORCID: 0000-0002-7362-7176, Masters, Colin L ORCID: 0000-0003-3072-7940, Cappai, Roberto ORCID: 0000-0002-9505-8496 and Hill, Andrew F ORCID: 0000-0001-5581-2354 (2010) Residues surrounding the glycosylphosphatidylinositol anchor attachment site of PrP modulate prion infection: insight from the resistance of rabbits to prion disease. Journal of Virology, 84 (13). pp. 6678-6686. ISSN 0022-538X

Harrison, Christopher F, Lawson, Victoria A ORCID: 0000-0002-7362-7176, Coleman, Bradley M, Kim, Y-S, Masters, Colin L ORCID: 0000-0003-3072-7940, Cappai, Roberto ORCID: 0000-0002-9505-8496, Barnham, Kevin J ORCID: 0000-0003-1164-9465 and Hill, Andrew F ORCID: 0000-0001-5581-2354 (2010) Conservation of a glycine-rich region in the prion protein is required for uptake of prion infectivity. Journal of Biological Chemistry, 285 (26). pp. 20213-20223. ISSN 0021-9258

Perreau, Victoria M, Orchard, Sandra, Adlard, Paul A, Bellingham, Shayne A ORCID: 0000-0001-5657-7413, Cappai, Roberto ORCID: 0000-0002-9505-8496, Ciccotosto, Giuseppe D, Cowie, Tiffany F, Crouch, Peter J, Duce, James A, Evin, Genevie`ve, Faux, Noel G, Hill, Andrew F ORCID: 0000-0001-5581-2354, Hung, Ya Hui, James, SA, Li, Qiao-Xin, Mok, Su San, Tew, Deborah J, White, Anthony R ORCID: 0000-0003-1802-9891, Bush, Ashley I ORCID: 0000-0001-8259-9069, Hermjakob, Henning and Masters, Colin L ORCID: 0000-0003-3072-7940 (2010) A domain level interaction network of amyloid precursor protein and Aβ of Alzheimer's disease. Proteomics, 10 (12). pp. 2377-2395. ISSN 1615-9853

Leong, Su Ling, Pham, Chi LL, Galatis, Denise, Fodero-Tavoletti, Michelle T, Perez, Keyla, Hill, Andrew F ORCID: 0000-0001-5581-2354, Masters, Colin L ORCID: 0000-0003-3072-7940, Ali, Feda E, Barnham, Kevin J ORCID: 0000-0003-1164-9465 and Cappai, Roberto ORCID: 0000-0002-9505-8496 (2009) Formation of dopamine-mediated α-synuclein-soluble oligomers requires methionine oxidation. Free Radical Biology and Medicine, 46 (10). pp. 1328-1337. ISSN 0891-5849

Pham, Chi LL, Leong, Su Ling, Ali, Feda E, Kenche, Vijaya B ORCID: 0000-0003-4424-4886, Hill, Andrew F ORCID: 0000-0001-5581-2354, Gras, Sally L ORCID: 0000-0002-4660-1245, Barnham, Kevin J ORCID: 0000-0003-1164-9465 and Cappai, Roberto ORCID: 0000-0002-9505-8496 (2009) Dopamine and the dopamine oxidation product 5,6-dihydroxylindole promote distinct on-pathway and off-pathway aggregation of α-synuclein in a pH-dependent manner. Journal of Molecular Biology, 387 (3). pp. 771-785. ISSN 0022-2836

Coleman, Bradley M, Nisbet, Rebecca M ORCID: 0000-0002-3751-9119, Han, Sen, Cappai, Roberto ORCID: 0000-0002-9505-8496, Hatters, Danny M ORCID: 0000-0002-9965-2847 and Hill, Andrew F ORCID: 0000-0001-5581-2354 (2009) Conformational detection of prion protein with biarsenical labeling and FlAsH fluorescence. Biochemical and Biophysical Research Communications, 380 (3). pp. 564-568. ISSN 0006-291X

Vella, Laura J ORCID: 0000-0002-1869-6291, Greenwood, Deanne LV, Cappai, Roberto ORCID: 0000-0002-9505-8496, Scheerlinck, Jean-Pierre Y ORCID: 0000-0002-8385-353X and Hill, Andrew F ORCID: 0000-0001-5581-2354 (2008) Enrichment of prion protein in exosomes derived from ovine cerebral spinal fluid. Veterinary Immunology and Immunopathology, 124 (3-4). pp. 385-393. ISSN 0165-2427

Chan, Sharon L, Kim, Woojin Scott, Kwok, John B, Hill, Andrew F ORCID: 0000-0001-5581-2354, Cappai, Roberto ORCID: 0000-0002-9505-8496, Rye, Kerry-Anne and Garner, Brett (2008) ATP-binding cassette transporter A7 regulates processing of amyloid precursor protein in vitro. Journal of Neurochemistry, 106 (2). pp. 793-804. ISSN 0022-3042

Lawson, Victoria A ORCID: 0000-0002-7362-7176, Vella, Laura J ORCID: 0000-0002-1869-6291, Stewart, James D, Sharples, Robyn A, Klemm, Helen MJ, Machalek, Dorothy, Masters, Colin L ORCID: 0000-0003-3072-7940, Cappai, Roberto ORCID: 0000-0002-9505-8496, Collins, Steven J and Hill, Andrew F ORCID: 0000-0001-5581-2354 (2008) Mouse-adapted sporadic human Creutzfeldt-Jakob disease prions propagate in cell culture. International Journal of Biochemistry and Cell Biology, 40 (12). pp. 2793-2801. ISSN 1357-2725

Albanese, Valeria ORCID: 0000-0002-9643-7519, Lawson, Victoria A ORCID: 0000-0002-7362-7176, Hill, Andrew F ORCID: 0000-0001-5581-2354, Cappai, Roberto ORCID: 0000-0002-9505-8496, Di Guardo, Giovanni, Staikopoulos, Vasiliki, Thacker, Michelle, Furness, John B ORCID: 0000-0002-0219-3438 and Chiocchetti, Roberto ORCID: 0000-0003-4448-6199 (2008) Evidence for prion protein expression in enteroglial cells of the myenteric plexus of mouse intestine. Autonomic Neuroscience: Basic and Clinical, 140 (1-2). pp. 17-23. ISSN 1566-0702

Smith, David P, Tew, Deborah J, Hill, Andrew F ORCID: 0000-0001-5581-2354, Bottomley, Stephen P, Masters, Colin L ORCID: 0000-0003-3072-7940, Barnham, Kevin J ORCID: 0000-0003-1164-9465 and Cappai, Roberto ORCID: 0000-0002-9505-8496 (2008) Formation of a high affinity lipid-binding intermediate during the early aggregation phase of α-synuclein. Biochemistry, 47 (5). pp. 1425-1434. ISSN 0006-2960

Vella, Laura, Sharples, Robyn A, Nisbet, Rebecca M, Cappai, Roberto ORCID: 0000-0002-9505-8496 and Hill, Andrew F ORCID: 0000-0001-5581-2354 (2007) The role of exosomes in the processing of proteins associated with neurodegenerative diseases. European Biophysics Journal, 37. pp. 323-332. ISSN 0175-7571

Vella, Laura, Sharples, Robyn A, Lawson, Victoria A ORCID: 0000-0002-7362-7176, Masters, Colin L ORCID: 0000-0003-3072-7940, Cappai, Roberto ORCID: 0000-0002-9505-8496 and Hill, Andrew F ORCID: 0000-0001-5581-2354 (2007) Packaging of prions into exosomes is associated with a novel pathway of PrP processing. Journal of Pathology, 211 (5). pp. 582-590. ISSN 0022-3417

Barnham, Kevin J, Cappai, Roberto ORCID: 0000-0002-9505-8496, Beyreuther, Konrad, Masters, Colin L ORCID: 0000-0003-3072-7940 and Hill, Andrew F ORCID: 0000-0001-5581-2354 (2006) Delineating common molecular mechanisms in Alzheimer's and prion diseases. Trends in Biochemical Sciences, 31 (8). pp. 465-472. ISSN 0968-0004

Yuan, Fang F, Biffin, Sandra, Brazier, Marcus W, Suarez, Monica, Cappai, Roberto ORCID: 0000-0002-9505-8496, Hill, Andrew F ORCID: 0000-0001-5581-2354, Collins, Steven J, Sullivan, John S, Middleton, Deborah, Multhaup, Gerd, Geczy, AF and Masters, Colin L ORCID: 0000-0003-3072-7940 (2005) Detection of prion epitopes on PrPc and PrPsc of transmissible spongiform encephalopathies using specific monoclonal antibodies to PrP. Immunology and Cell Biology, 83 (6). pp. 632-637. ISSN 0818-9641

Brazier, Marcus W, Lewis, Victoria A, Ciccotosto, Giuseppe D, Klug, Genevieve M, Lawson, Victoria A ORCID: 0000-0002-7362-7176, Cappai, Roberto ORCID: 0000-0002-9505-8496, Ironside, James W, Masters, Colin L ORCID: 0000-0003-3072-7940, Hill, Andrew F ORCID: 0000-0001-5581-2354, White, Anthony R ORCID: 0000-0003-1802-9891 and Collins, Steven J (2005) Correlative studies support lipid peroxidation is linked to PrPres propagation as an early primary pathogenic event in prion disease. Brain Research Bulletin, 68 (5). pp. 346-354. ISSN 0361-9230

Cappai, Roberto ORCID: 0000-0002-9505-8496, Leek, Su-Ling, Tew, Deborah J, Williamson, Nicholas A ORCID: 0000-0002-2173-3452, Smith, David P, Galatis, Denise, Sharples, Robyn A, Curtain, Cyril C, Ali, Feda E, Cherny, Robert A, Culvenor, Janetta G, Bottomley, Stephen P, Masters, Colin L ORCID: 0000-0003-3072-7940, Barnham, Kevin J ORCID: 0000-0003-1164-9465 and Hill, Andrew F ORCID: 0000-0001-5581-2354 (2005) Dopamine promotes α-synuclein aggregation into SDS-resistant soluble oligomers via a distinct folding pathway. FASEB Journal, 19 (10). pp. 1377-1379. ISSN 0892-6638

White, Anthony R ORCID: 0000-0003-1802-9891, Guirguis, Ronald, Brazier, Marcus W, Jobling, Michael F, Hill, Andrew F ORCID: 0000-0001-5581-2354, Beyreuther, Konrad, Barrow, Colin J, Masters, Colin L ORCID: 0000-0003-3072-7940, Collins, Steven J and Cappai, Roberto ORCID: 0000-0002-9505-8496 (2002) Sublethal concentrations of prion peptide PrP106-126 or the amyloid beta peptide of Alzheimer's disease activates expression of proapoptotic markers in primary cortical neurons. Neurobiology of Disease, 8 (2). pp. 299-316. ISSN 0969-9961

Book

Hill, Andrew F ORCID: 0000-0001-5581-2354, Barnham, Kevin J ORCID: 0000-0003-1164-9465, Bottomley, Stephen P and Cappai, Roberto ORCID: 0000-0002-9505-8496, eds. (2011) Protein folding, misfolding, and disease: methods and protocols. Methods in Molecular Biology, 752 . Humana Totowa, NJ, USA, pp. 1-249.

Book Section

Miles, Luke A, Crespi, Gabriela AN, Han, Sen, Hill, Andrew F ORCID: 0000-0001-5581-2354 and Parker, Michael W (2011) An Escherichia coli Cell-Free System for Recombinant Protein Synthesis on a Milligram Scale. In: Protein Folding, Misfolding, and Disease: Methods and Protocols. Hill, Andrew F, Barnham, Kevin J, Bottomley, SP and Cappai, Roberto, eds. Methods in Molecular Biology, 752 . Springer, USA, pp. 17-28.

Vella, Laura, Hill, Andrew F ORCID: 0000-0001-5581-2354 and Cappai, Roberto ORCID: 0000-0002-9505-8496 (2005) Mechanisms of prion toxicity and their relationship to prion infectivity. In: Neurodegeneration and Prion Disease. Springer, New York, USA, pp. 217-240.