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Jones, Patrice ORCID: 0000-0002-4948-1445, Voisin, Sarah ORCID: 0000-0002-4074-7083, Nolan, Brendan J ORCID: 0000-0001-8836-165X, Landen, Shanie, Jacques, Macsue ORCID: 0000-0002-4337-7022, Newell, Beau, Zwickl, Sav, Cook, Teddy, Wong, Alex ORCID: 0000-0002-3666-5261, Ginger, Ariel, Palmer, Andrew, Garnham, Andrew, Alvarez-Romero, Javier, Mohandas, Namitha, Seale, Kirsten, Cheung, Ada and Eynon, Nir ORCID: 0000-0003-4046-8276 (2022) Uncovering the effects of gender affirming hormone therapy on skeletal muscle and epigenetics: protocol for a prospective matched cohort study in transgender individuals (the GAME study). BMJ open, 12 (5). ISSN 2044-6055