Article

Apostolopoulos, Vasso ORCID: 0000-0001-6788-2771, Georgiou, Nikitas, Tzeli, Demeter, Mavromoustakos, Thomas ORCID: 0000-0001-5309-992X, Moore, Graham J, Kelaidonis, Konstantinos, Matsoukas, Minos-Timotheos ORCID: 0000-0002-4642-8163, Tsiodras, Sotirios ORCID: 0000-0002-0463-4321, Swiderski, Jordan ORCID: 0000-0002-3613-2406, Gadanec, Laura Kate ORCID: 0000-0002-4801-8061, Zulli, Anthony ORCID: 0000-0002-2660-078X, Chasapis, Christos T ORCID: 0000-0002-8728-6245 and Matsoukas, John ORCID: 0000-0001-5554-2964 (2024) Density functional theory and enzyme studies support interactions between angiotensin receptor blockers and angiotensin converting enzyme-2: Relevance to coronavirus 2019. Bioorganic Chemistry, 150. ISSN 0045-2068

Rodi, Maria ORCID: 0000-0001-6578-0851, de Lastic, Anne-Lise ORCID: 0000-0002-3152-4777, Panagoulias, Ioannis, Aggeletopoulou, Ioanna ORCID: 0000-0003-4489-1485, Kelaidonis, Kostas, Matsoukas, John ORCID: 0000-0001-5554-2964, Apostolopoulos, Vasso ORCID: 0000-0001-6788-2771 and Mouzaki, Athanasia ORCID: 0000-0001-5548-7002 (2024) Myelin Oligodendrocyte Glycoprotein (MOG)35–55 Mannan Conjugate Induces Human T-Cell Tolerance and Can Be Used as a Personalized Therapy for Multiple Sclerosis. International Journal of Molecular Sciences, 25 (11). ISSN 1661-6596 (print) 1422-0067 (online)

Moore, Graham J, Ridway, Harry, Gadanec, Laura Kate ORCID: 0000-0002-4801-8061, Apostolopoulos, Vasso ORCID: 0000-0001-6788-2771, Zulli, Anthony ORCID: 0000-0002-2660-078X, Swiderski, Jordan ORCID: 0000-0002-3613-2406, Kelaidonis, Konstantinos, Vidali, Veroniki P ORCID: 0000-0001-9020-8726, Matsoukas, Minos-Timotheos ORCID: 0000-0002-4642-8163, Chasapis, Christos T ORCID: 0000-0002-8728-6245 and Matsoukas, John ORCID: 0000-0001-5554-2964 (2024) Structural Features Influencing the Bioactive Conformation of Angiotensin II and Angiotensin A: Relationship between Receptor Desensitization, Addiction, and the Blood–Brain Barrier. International Journal of Molecular Sciences, 25 (11). ISSN 1422-0067

Ridgway, Harry, Moore, Graham J, Gadanec, Laura Kate ORCID: 0000-0002-4801-8061, Zulli, Anthony ORCID: 0000-0002-2660-078X, Apostolopoulos, Vasso ORCID: 0000-0001-6788-2771, Hoffmann, Weronika, Węgrzyn, Katarzyna, Vassilaki, Niki, Mpekoulis, George, Zouridakis, Marios, Giastas, Petros, Vidali, Veroniki P ORCID: 0000-0001-9020-8726, Kelaidonis, Konstantinos, Matsoukas, Minos-Timotheos ORCID: 0000-0002-4642-8163, Dimitriou, Marios, Mavromoustakos, Thomas ORCID: 0000-0001-5309-992X, Tsiodras, Sotirios ORCID: 0000-0002-0463-4321, Gorgoulis, Vassilis G, Karakasiliotis, Ioannis, Chasapis, Christos T ORCID: 0000-0002-8728-6245 and Matsoukas, John ORCID: 0000-0001-5554-2964 (2024) Novel benzimidazole angiotensin receptor blockers with anti-SARS-CoV-2 activity equipotent to that of nirmatrelvir: computational and enzymatic studies. Expert Opinion on Therapeutic Targets, 28 (5). pp. 437-459. ISSN 1472-8222

Gadanec, Laura Kate ORCID: 0000-0002-4801-8061, Swiderski, Jordan ORCID: 0000-0002-3613-2406, Apostolopoulos, Vasso ORCID: 0000-0001-6788-2771, Kelaidonis, Konstantinos, Vidali, Veroniki P ORCID: 0000-0001-9020-8726, Canko, Aleksander, Moore, Graham J, Matsoukas, John ORCID: 0000-0001-5554-2964 and Zulli, Anthony ORCID: 0000-0002-2660-078X (2023) Existence of Quantum Pharmacology in Sartans: Evidence in Isolated Rabbit Iliac Arteries. International Journal of Molecular Sciences, 24 (24). ISSN 1661-6596 (print) 1422-0067 (online)

Ridgway, Harry, Orbell, John ORCID: 0000-0003-3485-5309, Matsoukas, Minos-Timotheos ORCID: 0000-0002-4642-8163, Kelaidonis, Konstantinos, Moore, Graham J, Tsiodras, Sotiris, Apostolopoulos, Vasso ORCID: 0000-0001-6788-2771, Chasapis, Christos T ORCID: 0000-0002-8728-6245, Gorgoulis, Vassilis G and Matsoukas, John ORCID: 0000-0001-5554-2964 (2023) W254 in furin functions as a molecular gate: elucidation of putative drug tunneling and docking by non-equilibrium molecular dynamics. Computational and Structural Biotechnology Journal. ISSN 2001-0370

Swiderski, Jordan ORCID: 0000-0002-3613-2406, Gadanec, Laura Kate ORCID: 0000-0002-4801-8061, Apostolopoulos, Vasso ORCID: 0000-0001-6788-2771, Moore, Graham J, Kelaidonis, Konstantinos, Matsoukas, John ORCID: 0000-0001-5554-2964 and Zulli, Anthony ORCID: 0000-0002-2660-078X (2023) Role of angiotensin II in cardiovascular diseases: introducing bisartans as a novel therapy for Coronavirus 2019. Biomolecules, 13 (5). ISSN 2218-273X

Hossain, Md Kamal, Davidson, Majid ORCID: 0000-0002-3241-6444, Feehan, Jack ORCID: 0000-0002-9627-1299, Deraos, George, Nurgali, Kulmira ORCID: 0000-0002-2597-6929, Matsoukas, John ORCID: 0000-0001-5554-2964 and Apostolopoulos, Vasso ORCID: 0000-0001-6788-2771 (2023) Development of methamphetamine conjugated vaccine through hapten design: in vitro and in vivo characterization. Vaccines, 11 (2). ISSN 2076-393X

Ridgway, Harry, Ntallis, Charalampos ORCID: 0000-0002-4189-5803, Chasapis, Christos T ORCID: 0000-0002-8728-6245, Kelaidonis, Konstantinos, Matsoukas, Minos-Timotheos ORCID: 0000-0002-4642-8163, Plotas, Panagiotis, Apostolopoulos, Vasso ORCID: 0000-0001-6788-2771, Moore, Graham, Tsiodras, Sotirios ORCID: 0000-0002-0463-4321, Paraskevis, Dimitrios ORCID: 0000-0001-6167-7152, Mavromoustakos, Thomas ORCID: 0000-0001-5309-992X and Matsoukas, John ORCID: 0000-0001-5554-2964 (2023) Molecular epidemiology of SARS-CoV-2: the dominant role of arginine in mutations and infectivity. Viruses, 15 (2). ISSN 1999-4915

Kate Gadanec, Laura, Qaradakhi, Tawar, Renee McSweeney, Kristen, Matsoukas, John ORCID: 0000-0001-5554-2964, Apostolopoulos, Vasso ORCID: 0000-0001-6788-2771, Burrell, Louise M and Zulli, Anthony ORCID: 0000-0002-2660-078X (2022) Diminazene aceturate uses different pathways to induce relaxation in healthy and atherogenic blood vessels. Biochemical Pharmacology, 208. ISSN 0006-2952

Kamal Hossain, Md, Davidson, Majid ORCID: 0000-0002-3241-6444, Feehan, Jack ORCID: 0000-0002-9627-1299, Deraos, George ORCID: 0000-0003-0724-5222, Nurgali, Kulmira ORCID: 0000-0002-2597-6929, Matsoukas, John ORCID: 0000-0001-5554-2964 and Apostolopoulos, Vasso ORCID: 0000-0001-6788-2771 (2022) Development and characterization of a novel conjugated methamphetamine vaccine. Vaccine, 40 (41). pp. 5882-5891. ISSN 0264-410X

Apostolopoulos, Vasso ORCID: 0000-0001-6788-2771, Bojarska, Joanna ORCID: 0000-0001-9190-6913, Feehan, Jack ORCID: 0000-0002-9627-1299, Matsoukas, John ORCID: 0000-0001-5554-2964 and Wolf, Wojciech (2022) Smart therapies against global pandemics: A potential of short peptides. Frontiers in Pharmacology, 13. ISSN 1663-9812

Matsoukas, John ORCID: 0000-0001-5554-2964, Gadanec, Laura Kate ORCID: 0000-0002-4801-8061, Zulli, Anthony ORCID: 0000-0002-2660-078X, Apostolopoulos, Vasso ORCID: 0000-0001-6788-2771, Kelaidonis, Konstantinos, Ligielli, Irene, Moschovou, Kalliopi, Georgiou, Nikitas, Plotas, Panagiotis, Chasapis, Christos T ORCID: 0000-0002-8728-6245, Moore, Graham, Ridgway, Harry and Mavromoustakos, Thomas ORCID: 0000-0001-5309-992X (2022) Diminazene aceturate reduces angiotensin II constriction and interacts with the spike protein of severe acute respiratory syndrome Coronavirus 2. Biomedicines, 10 (7). ISSN 2227-9059

Ridgway, Harry, Chasapis, Christos T ORCID: 0000-0002-8728-6245, Kelaidonis, Konstantinos, Ligielli, Irene, Moore, Graham J, Gadanec, Laura Kate ORCID: 0000-0002-4801-8061, Zulli, Anthony ORCID: 0000-0002-2660-078X, Apostolopoulos, Vasso ORCID: 0000-0001-6788-2771, Mavromoustakos, Thomas ORCID: 0000-0001-5309-992X and Matsoukas, John ORCID: 0000-0001-5554-2964 (2022) Understanding the driving forces that trigger mutations in SARS‐CoV‐2: mutational energetics and the role of arginine blockers in COVID‐19 therapy. Viruses, 14 (5). ISSN 1999-4915

Ridgway, Harry, Moore, Graham J, Mavromoustakos, Thomas, Tsiodras, Sotirios, Ligielli, Irene, Kelaidonis, Konstantinos, Chasapis, Christos T, Gadanec, Laura Kate ORCID: 0000-0002-4801-8061, Zulli, Anthony ORCID: 0000-0002-2660-078X, Apostolopoulos, Vasso ORCID: 0000-0001-6788-2771, Petty, Russell, Karakasiliotis, Ioannis, Gorgoulis, Vassilis G and Matsoukas, John ORCID: 0000-0001-5554-2964 (2022) Discovery of a new generation of angiotensin receptor blocking drugs: receptor mechanisms and in silico binding to enzymes relevant to SARS-CoV-2. Computational and Structural Biotechnology Journal, 20. pp. 2091-2111. ISSN 2001-0370

Chasapis, Christos T ORCID: 0000-0002-8728-6245, Kelaidonis, Konstantinos, Ridgway, Harry, Apostolopoulos, Vasso ORCID: 0000-0001-6788-2771 and Matsoukas, John ORCID: 0000-0001-5554-2964 (2022) The Human Myelin Proteome and Sub-Metalloproteome Interaction Map: Relevance to Myelin-Related Neurological Diseases. Brain Sciences, 12 (4). ISSN 2076-3425

Matsoukas, John ORCID: 0000-0001-5554-2964, Deraos, George, Kelaidonis, Kostas, Hossain, Md Kamal, Feehan, Jack ORCID: 0000-0002-9627-1299, Tzakos, AG ORCID: 0000-0001-6391-0288, Matsoukas, Elizabeth, Topoglidis, E ORCID: 0000-0002-0009-9309 and Apostolopoulos, Vasso ORCID: 0000-0001-6788-2771 (2021) Myelin peptide–mannan conjugate multiple sclerosis vaccines: conjugation efficacy and stability of vaccine ingredient. Vaccines, 9 (12). ISSN 2076-393X

Matsoukas, John ORCID: 0000-0001-5554-2964, Ligielli, Irene, Chasapis, Christos T, Kelaidonis, Konstantinos, Apostolopoulos, Vasso ORCID: 0000-0001-6788-2771 and Mavromoustakos, Thomas (2021) Novel Approaches in the Immunotherapy of Multiple Sclerosis: Cyclization of Myelin Epitope Peptides and Conjugation with Mannan. Brain Sciences, 11 (12). ISSN 2076-3425

Moore, Graham J, Pires, Jose M, Kelaidonis, Konstantinos, Gadanec, Laura Kate ORCID: 0000-0002-4801-8061, Zulli, Anthony ORCID: 0000-0002-2660-078X, Apostolopoulos, Vasso ORCID: 0000-0001-6788-2771 and Matsoukas, John (2021) Receptor Interactions of Angiotensin II and Angiotensin Receptor Blockers—Relevance to COVID-19. Biomolecules, 11 (7). ISSN 2218-273X

Matsoukas, John, Apostolopoulos, Vasso ORCID: 0000-0001-6788-2771, Zulli, Anthony ORCID: 0000-0002-2660-078X, Moore, Graham, Kelaidonis, Konstantinos, Moschovou, Kalliopi and Mavromoustakos, Thomas (2021) From Angiotensin II to Cyclic Peptides and Angiotensin Receptor Blockers (ARBS): Perspectives of ARBs in COVID-19 Therapy. Molecules, 26 (3). ISSN 1420-3049

Apostolopoulos, Vasso ORCID: 0000-0001-6788-2771, Bojarska, Joanna ORCID: 0000-0001-9190-6913, Chai, Tsun-Thai ORCID: 0000-0003-3716-1599, Elnagdy, Sherif ORCID: 0000-0003-1331-8977, Kaczmarek, Krzysztof ORCID: 0000-0001-8806-7792, Matsoukas, John ORCID: 0000-0001-5554-2964, New, Roger, Parang, Keykavous ORCID: 0000-0001-8600-0893, Lopez, Octavio Paredes ORCID: 0000-0003-1583-7631, Parhiz, Hamideh, Perera, Conrad O, Pickholz, Monica, Remko, Milan, Saviano, Michele, Skwarczynski, Mariusz, Tang, Yefeng, Wolf, Wojciech, Yoshiya, Taku, Zabrocki, Janusz, Zielenkiewicz, Piotr, Alkhazindar, Maha ORCID: 0000-0002-3244-9377, Barriga, Vanessa, Kelaidonis, Konstantinos, Sarasia, Elham Mousavinezhad and Toth, Istvan (2021) A global review on short peptides: Frontiers and perspectives. Molecules, 26 (2). pp. 1-45. ISSN 1420-3049

Deskoulidis, E, Petrouli, S, Apostolopoulos, Vasso ORCID: 0000-0001-6788-2771, Matsoukas, John and Topoglidis, E (2020) The use of electrochemical voltammetric techniques and high-pressure liquid chromatography to evaluate conjugation efficiency of multiple sclerosis peptide-carrier conjugates. Brain Sciences, 10 (9). ISSN 2076-3425

Dargahi, Narges, Matsoukas, John and Apostolopoulos, Vasso ORCID: 0000-0001-6788-2771 (2020) Streptococcus Thermophilus ST285 Alters Pro-Inflammatory to Anti-Inflammatory Cytokine Secretion Against Multiple Sclerosis Peptide in Mice. Brain Sciences, 10 (2). ISSN 2076-3425

Deraos, George, Kritsi, Eftichia, Matsoukas, Minos-Timotheos, Christopoulou, Konstantina, Kalbacher, Hubert, Zoumpoulakis, Panagiotis, Apostolopoulos, Vasso ORCID: 0000-0001-6788-2771 and Matsoukas, John (2018) Design of Linear and Cyclic Mutant Analogues of Dirucotide Peptide (MBP82–98) against Multiple Sclerosis: Conformational and Binding Studies to MHC Class II. Brain Sciences, 8 (12). ISSN 2076-3425

Qaradakhi, Tawar, Matsoukas, Minos-Timotheos ORCID: 0000-0002-4642-8163, Hayes, Alan ORCID: 0000-0003-1398-3694, Rybalka, Emma ORCID: 0000-0002-4854-0036, Caprnda, Martin, Rimarova, Kvetoslava, Sepsi, Milan, Büsselberg, Dietrich, Kruzliak, Peter, Matsoukas, John ORCID: 0000-0001-5554-2964, Apostolopoulos, Vasso ORCID: 0000-0001-6788-2771 and Zulli, Anthony ORCID: 0000-0002-2660-078X (2017) Alamandine reverses hyperhomocysteinemia-induced vascular dysfunction via PKA-dependent mechanisms. Cardiovascular Therapeutics, 35 (6). ISSN 1755-5914

Book Section

Zoupanou, Nikoletta, Georgiou, Nikitas, Moschovou, Kalliopi, Chasapis, Christos T ORCID: 0000-0002-8728-6245, Kelaidonis, Konstantinos, Chavda, Vivek P ORCID: 0000-0002-7701-8597, Mavromoustakos, Thomas ORCID: 0000-0001-5309-992X, Matsoukas, John ORCID: 0000-0001-5554-2964 and Apostolopoulos, Vasso ORCID: 0000-0001-6788-2771 (2024) Peptide-based vaccines and altered peptide ligands: Multiple sclerosis paving the way. In: Advanced Vaccination Technologies for Infectious and Chronic Diseases: A Guide to Vaccinology. Chavda, VP, Apostolopoulos, V and Vora, LK, eds. Academic Press, pp. 63-72.

Conference or Workshop Item

Rostami, Mohamad, Apostolopoulos, Vasso ORCID: 0000-0001-6788-2771 and Matsoukas, John (2019) Multiple sclerosis research in Greece: Targeting clinical trials. In: 19th Medicinal Chemistry Conference: Drugs Discovery and Design, 20-22 September 2018, Amaliada, Greece.

Tseveleki, V, Kanistras, I, Apostolopoulos, Vasso ORCID: 0000-0001-6788-2771, Matsoukas, John and Probert, L (2019) Therapeutic approaches in multiple sclerosis mouse models using mannan-conjugated peptides. In: 19th Medicinal Chemistry Conference: Drugs Discovery and Design, 20-22 September 2018, Amaliada, Greece.