Sharples, Robyn A
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Sisquella, Xavier, Ofir-Birin, Yifat, Pimentel, Matthew A, Cheng, Lesley, Abou Karam, Paula, Sampaio, Natalia G, Penington, Jocelyn Sietsma, Connolly, Dympna, Giladi, Tal, Scicluna, Benjamin J, Sharples, Robyn A, Waltmann, Andreea, Avni, Dror, Schwartz, Eli, Schofield, Louis, Porat, Ziv, Hansen, Diana S, Papenfuss, Anthony T, Eriksson, Emily M, Gerlic, Motti, Hill, Andrew F ORCID: 0000-0001-5581-2354, Bowie, Andrew G and Regev-Rudzki, Neta
(2017)
Malaria parasite DNA-harbouring vesicles activate cytosolic immune sensors.
Nature Communications, 8.
ISSN 2041-1723
Lunavat, Taral R, Cheng, Lesley ORCID: 0000-0002-8075-6144, Einarsdottir, Berglind O, Bagge, Roger Olofsson, Muralidharan, Somsundar Veppil, Sharples, Robyn A, Lässer, Cecilia, Gho, Yong Song, Hill, Andrew F
ORCID: 0000-0001-5581-2354, Nilsson, Jonas A and Lötvall, Jan
ORCID: 0000-0001-9195-9249
(2017)
BRAFV600 inhibition alters the microRNA cargo in the vesicular secretome of malignant melanoma cells.
Proceedings of the National Academy of Sciences of the United States of America, 114 (29).
pp. 5930-5939.
ISSN 0027-8424
Quek, Camelia ORCID: 0000-0002-1244-961X, Bellingham, Shayne A
ORCID: 0000-0001-5657-7413, Jung, Chol-Hee
ORCID: 0000-0002-2992-3162, Scicluna, Benjamin J
ORCID: 0000-0001-6828-9910, Shambrook, Mitch, Sharples, Robyn A, Cheng, Lesley
ORCID: 0000-0002-8075-6144 and Hill, Andrew F
ORCID: 0000-0001-5581-2354
(2017)
Defining the purity of exosomes required for diagnostic profiling of small RNA suitable for biomarker discovery.
RNA Biology, 14 (2).
pp. 245-258.
ISSN 1547-6286
Cheng, Lesley ORCID: 0000-0002-8075-6144, Quek, Camelia YJ, Hung, Lin W, Sharples, Robyn A, Sherratt, Nicki A, Barnham, Kevin J
ORCID: 0000-0003-1164-9465 and Hill, Andrew F
ORCID: 0000-0001-5581-2354
(2016)
Gene dysregulation is restored in the Parkinson's disease MPTP neurotoxic mice model upon treatment of the therapeutic drug CuII (atsm).
Scientific Reports, 6.
ISSN 2045-2322
Lunavat, Taral R, Cheng, Lesley ORCID: 0000-0002-8075-6144, Kim, Dae-Kyum, Bhadury, Joydeep, Jang, Su Chul, Lässer, Cecilia, Sharples, Robyn A, López, Marcela Dávila, Nilsson, Jonas A, Gho, Yong Song, Hill, Andrew F
ORCID: 0000-0001-5581-2354 and Lötvall, Jan
(2015)
Small RNA deep sequencing discriminates subsets of extracellular vesicles released by melanoma cells – evidence of unique microRNA cargos.
RNA Biology, 12 (8).
pp. 810-823.
ISSN 1547-6286
Cheng, Lesley, Sharples, Robyn A, Scicluna, Benjamin J and Hill, Andrew F ORCID: 0000-0001-5581-2354
(2014)
Exosomes provide a protective and enriched source of miRNA for biomarker profiling compared to intracellular and cell-free blood.
Journal of Extracellular Vesicles, 3 (1).
ISSN 2001-3078
Chia, Pei Zhi Cheryl, Toh, Wei Hong, Sharples, Robyn A, Gasnereau, Isabelle, Hill, Andrew F ORCID: 0000-0001-5581-2354 and Gleeson, Paul
(2013)
Intracellular itinerary of internalised β-secretase, BACE1, and its potential impact on β-amyloid peptide biogenesis.
Traffic, 14 (9).
pp. 997-1013.
ISSN 1398-9219
Lawson, Victoria A ORCID: 0000-0002-7362-7176, Vella, Laura J
ORCID: 0000-0002-1869-6291, Stewart, James D, Sharples, Robyn A, Klemm, Helen MJ, Machalek, Dorothy, Masters, Colin L
ORCID: 0000-0003-3072-7940, Cappai, Roberto
ORCID: 0000-0002-9505-8496, Collins, Steven J and Hill, Andrew F
ORCID: 0000-0001-5581-2354
(2008)
Mouse-adapted sporadic human Creutzfeldt-Jakob disease prions propagate in cell culture.
International Journal of Biochemistry and Cell Biology, 40 (12).
pp. 2793-2801.
ISSN 1357-2725
Sharples, Robyn A, Vella, Laura, Nisbet, Rebecca M, Naylor, Ryan, Perez, Keyla, Barnham, Kevin J, Masters, Colin L ORCID: 0000-0003-3072-7940 and Hill, Andrew F
ORCID: 0000-0001-5581-2354
(2008)
Inhibition of γ-secretase causes increased secretion of amyloid precursor protein C-terminal fragments in association with exosomes.
FASEB Journal, 22 (5).
pp. 1469-1478.
ISSN 0892-6638
Donnelly, Paul S, Caragounis, Aphrodite, Du, Tai, Laughton, Katrina M, Volitakis, Irene, Cherny, Robert A, Sharples, Robyn A, Hill, Andrew F ORCID: 0000-0001-5581-2354, Li, Qiao-Xin, Masters, Colin L
ORCID: 0000-0003-3072-7940, Barnham, Kevin J and White, Anthony R
ORCID: 0000-0003-1802-9891
(2008)
Selective intracellular release of copper and zinc ions from bis(thiosemicarbazonato) complexes reduces levels of Alzheimer disease amyloid-β peptide.
Journal of Biological Chemistry, 283 (8).
pp. 4568-4577.
ISSN 0021-9258
Price, Katherine A, Filiz, Gulay, Caragounis, Aphrodite, Du, Tai, Laughton, Katrina M, Masters, Colin L ORCID: 0000-0003-3072-7940, Sharples, Robyn A, Hill, Andrew F
ORCID: 0000-0001-5581-2354, Li, Qiao-Xin, Donnelly, Paul S, Barnham, Kevin J
ORCID: 0000-0003-1164-9465, Crouch, Peter J and White, Anthony R
ORCID: 0000-0003-1802-9891
(2008)
Activation of epidermal growth factor receptor by metal-ligand complexes decreases levels of extracellular amyloid beta peptide.
International Journal of Biochemistry and Cell Biology, 40 (9).
pp. 1901-1917.
ISSN 1357-2725
Vella, Laura, Sharples, Robyn A, Nisbet, Rebecca M, Cappai, Roberto ORCID: 0000-0002-9505-8496 and Hill, Andrew F
ORCID: 0000-0001-5581-2354
(2007)
The role of exosomes in the processing of proteins associated with neurodegenerative diseases.
European Biophysics Journal, 37.
pp. 323-332.
ISSN 0175-7571
Caragounis, Aphrodite, Du, Tai, Filiz, Gulay, Laughton, Katrina M, Volitakis, Irene, Sharples, Robyn A, Cherny, Robert A, Masters, Colin L ORCID: 0000-0003-3072-7940, Drew, Simon C, Hill, Andrew F
ORCID: 0000-0001-5581-2354, Li, Qiao-Xin, Crouch, Peter J, Barnham, Kevin J
ORCID: 0000-0003-1164-9465 and White, Anthony R
ORCID: 0000-0003-1802-9891
(2007)
Differential modulation of Alzheimer's disease amyloid β-peptide accumulation by diverse classes of metal ligands.
Biochemical Journal, 407 (3).
pp. 435-450.
ISSN 0264-6021
Vella, Laura, Sharples, Robyn A, Lawson, Victoria A ORCID: 0000-0002-7362-7176, Masters, Colin L
ORCID: 0000-0003-3072-7940, Cappai, Roberto
ORCID: 0000-0002-9505-8496 and Hill, Andrew F
ORCID: 0000-0001-5581-2354
(2007)
Packaging of prions into exosomes is associated with a novel pathway of PrP processing.
Journal of Pathology, 211 (5).
pp. 582-590.
ISSN 0022-3417
White, Anthony R ORCID: 0000-0003-1802-9891, Du, Tai, Laughton, Katrina M, Volitakis, Irene, Sharples, Robyn A, Xilinas, Michael E, Hoke, David E, Holsinger, RM Damian
ORCID: 0000-0002-4447-0835, Evin, Genevie`ve, Cherny, Robert A, Hill, Andrew F
ORCID: 0000-0001-5581-2354, Barnham, Kevin J
ORCID: 0000-0003-1164-9465, Li, Qiao-Xin, Bush, Ashley I
ORCID: 0000-0001-8259-9069 and Masters, Colin L
ORCID: 0000-0003-3072-7940
(2006)
Degradation of the Alzheimer disease amyloid β-peptide by metal-dependent up-regulation of metalloprotease activity.
Journal of Biological Chemistry, 281 (26).
pp. 17670-17680.
ISSN 0021-9258
Cappai, Roberto ORCID: 0000-0002-9505-8496, Leek, Su-Ling, Tew, Deborah J, Williamson, Nicholas A
ORCID: 0000-0002-2173-3452, Smith, David P, Galatis, Denise, Sharples, Robyn A, Curtain, Cyril C, Ali, Feda E, Cherny, Robert A, Culvenor, Janetta G, Bottomley, Stephen P, Masters, Colin L
ORCID: 0000-0003-3072-7940, Barnham, Kevin J
ORCID: 0000-0003-1164-9465 and Hill, Andrew F
ORCID: 0000-0001-5581-2354
(2005)
Dopamine promotes α-synuclein aggregation into SDS-resistant soluble oligomers via a distinct folding pathway.
FASEB Journal, 19 (10).
pp. 1377-1379.
ISSN 0892-6638