Yeast-based process for production of I-pac
Smallridge, Andrew John, Trewhella, Maurice Arthur, Wilkinson, Kylie Anne (2006) Yeast-based process for production of I-pac. United States Patent 7063969.
Abstract
The invention provides a method of synthesis of a substituted or unsubstituted carbinol compound, comprising the steps of subjecting the corresponding substituted or unsubstituted aromatic aldehyde to acyloin condensation mediated by yeast in the presence of either (a) a supereritical fluid or (b) a liquefied gas, and recovering the carbinol compound. Preferably the yeast is Saccharomyces cerevisiae. In a particularly preferred embodiment the aromatic aldehyde is benzaldehyde and the carbinol is phenylacetylcarbinol, according to the reaction (I): in which the benzaldehyde, the pyruvic acid, or both may optionally be substituted.
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Item type | Patent |
URI | https://vuir.vu.edu.au/id/eprint/1674 |
DOI | United States Patent 7063969 |
Official URL | http://www.freepatentsonline.com/7063969.html (external link) |
Subjects | Historical > RFCD Classification > 290000 Engineering and Technology Historical > Faculty/School/Research Centre/Department > School of Engineering and Science |
Keywords | yeast-based, i-pac, USP 7063969, supereritical fluid, liquefied gas |
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