Identifying and characterising ethanol tolerance genes of brewing yeast
Download
Download
Download
Full text for this resource is not available from the Research Repository.
Export
Bandara, Nayana (2013) Identifying and characterising ethanol tolerance genes of brewing yeast. PhD thesis, Victoria University.
Abstract
In today’s competitive environment breweries need to produce high quality alcoholic beverages in a time-efficient and cost-effective manner. This has led the use of modern technologies such as high-gravity brewing. However, the benefits of this approach are limited by the ethanol sensitivity of the S. cerevisiae strains. The current study identifies mechanisms contributing to ethanol tolerance in a commercial brewing strain ‘IND1’. This was achieved by creating an ethanol tolerant mutant of the strain and investigating differences between the parent and the mutant in their response to ethanol at a molecular level. Genes contributing to ethanol tolerance were identified and characterised by comparing gene expression profiles of the parent and mutant in the absence and presence of ethanol, using microarray analysis.
| Additional Information | Full-text unavailable due to Copyright restrictions |
| Item type | Thesis (PhD thesis) |
| URI | https://vuir.vu.edu.au/id/eprint/28818 |
| Subjects | Historical > FOR Classification > 0908 Food Sciences Current > Division/Research > College of Science and Engineering |
| Keywords | ethanol stress, ergosterol biosynthesis genes, strain performance, genetics, alcohol, cDNA, IND1, INDM phenotype, mutant, mutagenesis, transcription profiling, gene expression |
| Download/View statistics | View download statistics for this item |
CORE (COnnecting REpositories)