Carrier-mediated delivery of peptidic drugs for cancer therapy

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Dass, Crispin R and Choong, Peter F. M (2006) Carrier-mediated delivery of peptidic drugs for cancer therapy. Peptides, 27 (11). pp. 3020-3028. ISSN 0196-9781

Abstract

Protein and peptide drugs are used for treatment of a variety of ailments. However, their wider use has been hindered by issues such as poor bioavailability in vivo and the cost involved in producing these drugs. This review discusses the various carrier-mediated methods used for delivery of peptide and protein drugs, with emphasis on liposomal and microspherical drug delivery systems. A brief look at the types of peptidic drugs currently in use clinically, and a brief discourse on several novel ideas for better protein delivery systems for cancer therapy is included.

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Item type	Article
URI	https://vuir.vu.edu.au/id/eprint/7517
DOI	10.1016/j.peptides.2006.05.020
Official URL	http://dx.doi.org/10.1016/j.peptides.2006.05.020
Subjects	Historical > Faculty/School/Research Centre/Department > School of Biomedical and Health Sciences Historical > FOR Classification > 1112 Oncology and Carcinogenesis Historical > SEO Classification > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions)
Keywords	ResPubID21890. peptides, peptide drugs, protein, drug delivery, cancer, liposome, microparticles
Citations in Scopus	36 - View on Scopus
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