Carroll, Sean, Marshall, Paul, Borkoles, Erika, Ingle, Lee, Barke, Diane and Tan, Lip-Bun (2007) Efficacy of lifestyle intervention on peak exercise cardiac power output and reserve in premenopausal obese females: a randomised pilot study. International Journal of Cardiology, 119 (2). pp. 147-155. ISSN 0167-5273

Abstract

Clinically obese women have a two-fold increased risk for the development of heart failure. Among younger premenopausal females, obesity has been associated with cardiac remodelling and impaired resting systolic and diastolic function. However, few studies have evaluated cardiorespiratory and cardiac responses to maximal exertion among obese premenopausal females. A randomised pilot study was conducted to investigate the effects of a 3-month lifestyle intervention programme on weight management and maximal cardiorespiratory function in healthy clinically obese premenopausal females. Within this study, thirteen selected participants performed both graded and single-stage V . ˙O2peak exercise tests, the latter integrating the non-invasive measurement of cardiac output (CO2 rebreathing method), peak cardiac power output (CPOpeak) and physiological cardiac reserve. Six participants were randomly assigned to 3-months of lifestyle intervention and 7 served as waiting list controls.

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