Gadanec, Laura Kate
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Wang, Qian, Saadati, Saeede, Kabthymer, Robel Hussen, Gadanec, Laura Kate ORCID: 0000-0002-4801-8061, Lawton, Amy
ORCID: 0000-0002-7999-0873, Tripodi, Nicholas
ORCID: 0000-0001-5062-0409, Apostolopoulos, Vasso
ORCID: 0000-0001-6788-2771, de Courten, Barbora
ORCID: 0000-0001-8760-2511 and Feehan, Jack
ORCID: 0000-0002-9627-1299
(2024)
The impact of carnosine on biological ageing – A geroscience approach.
Maturitas, 189.
ISSN 0378-5122
Apostolopoulos, Vasso ORCID: 0000-0001-6788-2771, Georgiou, Nikitas, Tzeli, Demeter, Mavromoustakos, Thomas
ORCID: 0000-0001-5309-992X, Moore, Graham J, Kelaidonis, Konstantinos, Matsoukas, Minos-Timotheos
ORCID: 0000-0002-4642-8163, Tsiodras, Sotirios
ORCID: 0000-0002-0463-4321, Swiderski, Jordan
ORCID: 0000-0002-3613-2406, Gadanec, Laura Kate
ORCID: 0000-0002-4801-8061, Zulli, Anthony
ORCID: 0000-0002-2660-078X, Chasapis, Christos T
ORCID: 0000-0002-8728-6245 and Matsoukas, John
ORCID: 0000-0001-5554-2964
(2024)
Density functional theory and enzyme studies support interactions between angiotensin receptor blockers and angiotensin converting enzyme-2: Relevance to coronavirus 2019.
Bioorganic Chemistry, 150.
ISSN 0045-2068
Moore, Graham J, Ridway, Harry, Gadanec, Laura Kate ORCID: 0000-0002-4801-8061, Apostolopoulos, Vasso
ORCID: 0000-0001-6788-2771, Zulli, Anthony
ORCID: 0000-0002-2660-078X, Swiderski, Jordan
ORCID: 0000-0002-3613-2406, Kelaidonis, Konstantinos, Vidali, Veroniki P
ORCID: 0000-0001-9020-8726, Matsoukas, Minos-Timotheos
ORCID: 0000-0002-4642-8163, Chasapis, Christos T
ORCID: 0000-0002-8728-6245 and Matsoukas, John
ORCID: 0000-0001-5554-2964
(2024)
Structural Features Influencing the Bioactive Conformation of Angiotensin II and Angiotensin A: Relationship between Receptor Desensitization, Addiction, and the Blood–Brain Barrier.
International Journal of Molecular Sciences, 25 (11).
ISSN 1422-0067
Ridgway, Harry, Moore, Graham J, Gadanec, Laura Kate ORCID: 0000-0002-4801-8061, Zulli, Anthony
ORCID: 0000-0002-2660-078X, Apostolopoulos, Vasso
ORCID: 0000-0001-6788-2771, Hoffmann, Weronika, Węgrzyn, Katarzyna, Vassilaki, Niki, Mpekoulis, George, Zouridakis, Marios, Giastas, Petros, Vidali, Veroniki P
ORCID: 0000-0001-9020-8726, Kelaidonis, Konstantinos, Matsoukas, Minos-Timotheos
ORCID: 0000-0002-4642-8163, Dimitriou, Marios, Mavromoustakos, Thomas
ORCID: 0000-0001-5309-992X, Tsiodras, Sotirios
ORCID: 0000-0002-0463-4321, Gorgoulis, Vassilis G, Karakasiliotis, Ioannis, Chasapis, Christos T
ORCID: 0000-0002-8728-6245 and Matsoukas, John
ORCID: 0000-0001-5554-2964
(2024)
Novel benzimidazole angiotensin receptor blockers with anti-SARS-CoV-2 activity equipotent to that of nirmatrelvir: computational and enzymatic studies.
Expert Opinion on Therapeutic Targets, 28 (5).
pp. 437-459.
ISSN 1472-8222
Gadanec, Laura Kate ORCID: 0000-0002-4801-8061, Swiderski, Jordan
ORCID: 0000-0002-3613-2406, Apostolopoulos, Vasso
ORCID: 0000-0001-6788-2771, Kelaidonis, Konstantinos, Vidali, Veroniki P
ORCID: 0000-0001-9020-8726, Canko, Aleksander, Moore, Graham J, Matsoukas, John
ORCID: 0000-0001-5554-2964 and Zulli, Anthony
ORCID: 0000-0002-2660-078X
(2023)
Existence of Quantum Pharmacology in Sartans: Evidence in Isolated Rabbit Iliac Arteries.
International Journal of Molecular Sciences, 24 (24).
ISSN 1661-6596 (print) 1422-0067 (online)
Gadanec, Laura Kate ORCID: 0000-0002-4801-8061, Andersson, Ulf
ORCID: 0000-0003-0316-3860, Apostolopoulos, Vasso
ORCID: 0000-0001-6788-2771 and Zulli, Anthony
ORCID: 0000-0002-2660-078X
(2023)
Glycyrrhizic acid inhibits high-mobility group box-1 and homocysteine-induced vascular dysfunction.
Nutrients, 15 (14).
ISSN 2072-6643
Swiderski, Jordan ORCID: 0000-0002-3613-2406, Sakkal, Samy
ORCID: 0000-0003-0430-4012, Apostolopoulos, Vasso
ORCID: 0000-0001-6788-2771, Zulli, Anthony
ORCID: 0000-0002-2660-078X and Gadanec, Laura Kate
ORCID: 0000-0002-4801-8061
(2023)
Combination of taurine and black pepper extract as a treatment for cardiovascular and coronary artery diseases.
Nutrients, 15 (11).
ISSN 2072-6643
Swiderski, Jordan ORCID: 0000-0002-3613-2406, Gadanec, Laura Kate
ORCID: 0000-0002-4801-8061, Apostolopoulos, Vasso
ORCID: 0000-0001-6788-2771, Moore, Graham J, Kelaidonis, Konstantinos, Matsoukas, John
ORCID: 0000-0001-5554-2964 and Zulli, Anthony
ORCID: 0000-0002-2660-078X
(2023)
Role of angiotensin II in cardiovascular diseases: introducing bisartans as a novel therapy for Coronavirus 2019.
Biomolecules, 13 (5).
ISSN 2218-273X
Gadanec, Laura Kate ORCID: 0000-0002-4801-8061, McSweeney, Kristen, Kubatka, Peter, Caprnda, Martin, Gaspar, Ludovit, Prosecky, Robert, Dragasek, Jozef, Kruzliak, Peter, Apostolopoulos, Vasso
ORCID: 0000-0001-6788-2771 and Zulli, Anthony
ORCID: 0000-0002-2660-078X
(2023)
Angiotensin II constricts mouse iliac arteries: possible mechanism for aortic aneurysms.
Molecular and cellular biochemistry.
ISSN 0300-8177
McSweeney, Kristen, Gadanec, Laura Kate ORCID: 0000-0002-4801-8061, Kubatka, Peter, Caprnda, Martin, Gaspar, Ludovit, Prosecky, Robert, Delev, Delian, Kruzliak, Peter, Apostolopoulos, Vasso
ORCID: 0000-0001-6788-2771 and Zulli, Anthony
ORCID: 0000-0002-2660-078X
(2023)
Cisplatin treatment reduces contraction to angiotensin II by altering expression of angiotensin II receptors: a pilot study.
Molecular and Cellular Biochemistry.
ISSN 0300-8177
Matsoukas, John ORCID: 0000-0001-5554-2964, Gadanec, Laura Kate
ORCID: 0000-0002-4801-8061, Zulli, Anthony
ORCID: 0000-0002-2660-078X, Apostolopoulos, Vasso
ORCID: 0000-0001-6788-2771, Kelaidonis, Konstantinos, Ligielli, Irene, Moschovou, Kalliopi, Georgiou, Nikitas, Plotas, Panagiotis, Chasapis, Christos T
ORCID: 0000-0002-8728-6245, Moore, Graham, Ridgway, Harry and Mavromoustakos, Thomas
ORCID: 0000-0001-5309-992X
(2022)
Diminazene aceturate reduces angiotensin II constriction and interacts with the spike protein of severe acute respiratory syndrome Coronavirus 2.
Biomedicines, 10 (7).
ISSN 2227-9059
Ridgway, Harry, Chasapis, Christos T ORCID: 0000-0002-8728-6245, Kelaidonis, Konstantinos, Ligielli, Irene, Moore, Graham J, Gadanec, Laura Kate
ORCID: 0000-0002-4801-8061, Zulli, Anthony
ORCID: 0000-0002-2660-078X, Apostolopoulos, Vasso
ORCID: 0000-0001-6788-2771, Mavromoustakos, Thomas
ORCID: 0000-0001-5309-992X and Matsoukas, John
ORCID: 0000-0001-5554-2964
(2022)
Understanding the driving forces that trigger mutations in SARS‐CoV‐2: mutational energetics and the role of arginine blockers in COVID‐19 therapy.
Viruses, 14 (5).
ISSN 1999-4915
Ridgway, Harry, Moore, Graham J, Mavromoustakos, Thomas, Tsiodras, Sotirios, Ligielli, Irene, Kelaidonis, Konstantinos, Chasapis, Christos T, Gadanec, Laura Kate ORCID: 0000-0002-4801-8061, Zulli, Anthony
ORCID: 0000-0002-2660-078X, Apostolopoulos, Vasso
ORCID: 0000-0001-6788-2771, Petty, Russell, Karakasiliotis, Ioannis, Gorgoulis, Vassilis G and Matsoukas, John
ORCID: 0000-0001-5554-2964
(2022)
Discovery of a new generation of angiotensin receptor blocking drugs: receptor mechanisms and in silico binding to enzymes relevant to SARS-CoV-2.
Computational and Structural Biotechnology Journal, 20.
pp. 2091-2111.
ISSN 2001-0370
Moore, Graham J, Pires, Jose M, Kelaidonis, Konstantinos, Gadanec, Laura Kate ORCID: 0000-0002-4801-8061, Zulli, Anthony
ORCID: 0000-0002-2660-078X, Apostolopoulos, Vasso
ORCID: 0000-0001-6788-2771 and Matsoukas, John
(2021)
Receptor Interactions of Angiotensin II and Angiotensin Receptor Blockers—Relevance to COVID-19.
Biomolecules, 11 (7).
ISSN 2218-273X
Liskova, Alena, Samec, Marek, Koklesova, Lenka, Brockmueller, Aranka, Zhai, Kevin, Abdellatif, Basma, Siddiqui, Manaal, Biringer, Kamil, Kudela, Erik, Pec, Martin, Gadanec, Laura Kate ORCID: 0000-0002-4801-8061, Šudomová, Miroslava, Hassan, Sherif TS, Zulli, Anthony
ORCID: 0000-0002-2660-078X, Shakibaei, Mehdi, Giordano, Frank A, Büsselberg, Dietrich, Golubnitschaja, Olga and Kubatka, Peter
(2021)
Flavonoids as an efective sensitizer for anti‑cancer therapy:
insights into multi‑faceted mechanisms and applicability
towards individualized patient profles.
EPMA Journal, 12.
pp. 155-176.
ISSN 1878-5077
McSweeney, K ORCID: 0000-0003-4146-8251, Gadanec, Laura Kate
ORCID: 0000-0002-4801-8061, Qaradakhi, Tawar, Ali, Benazir, Zulli, Anthony
ORCID: 0000-0002-2660-078X and Apostolopoulos, Vasso
ORCID: 0000-0001-6788-2771
(2021)
Mechanisms of cisplatin‐induced acute kidney injury: pathological mechanisms, pharmacological interventions, and genetic mitigations.
Cancers, 13 (7).
ISSN 2072-6694
Gadanec, Laura Kate ORCID: 0000-0002-4801-8061, Qaradakhi, Tawar, McSweeney, K
ORCID: 0000-0003-4146-8251, Ashiana Ali, B, Zulli, Anthony
ORCID: 0000-0002-2660-078X and Apostolopoulos, Vasso
ORCID: 0000-0001-6788-2771
(2021)
Dual targeting of Toll-like receptor 4 and angiotensin-converting enzyme 2: a proposed approach to SARS-CoV-2 treatment.
Future Microbiology, 16 (4).
pp. 205-209.
ISSN 1746-0913
Gadanec, Laura Kate ORCID: 0000-0002-4801-8061, McSweeney, K
ORCID: 0000-0003-4146-8251, Qaradakhi, Tawar, Ali, Benazir, Zulli, Anthony
ORCID: 0000-0002-2660-078X and Apostolopoulos, Vasso
ORCID: 0000-0001-6788-2771
(2021)
Can SARS-CoV-2 virus use multiple receptors to enter host cells?
International Journal of Molecular Sciences, 22 (3).
ISSN 1661-6596
McSweeney, Kristen, Gadanec, Laura Kate ORCID: 0000-0002-4801-8061, Qaradakhi, Tawar, Gammune, Thushira Malindra, Kubatka, Peter, Caprnda, Martin, Fedotova, Julia, Radonak, Jozef, Kruzliak, Peter and Zulli, Anthony
ORCID: 0000-0002-2660-078X
(2020)
Imipridone enhances vascular relaxation via FOXO1 pathway.
Clinical and Experimental Pharmacology and Physiology, 47 (11).
pp. 1816-1823.
ISSN 0305-1870
Qaradakhi, Tawar, Gadanec, Laura Kate ORCID: 0000-0002-4801-8061, Matsoukas, J, Apostolopoulos, Vasso
ORCID: 0000-0001-6788-2771 and Zulli, Anthony
ORCID: 0000-0002-2660-078X
(2020)
Could DIZE be the answer to COVID-19?
Maturitas, 140.
pp. 83-84.
ISSN 0378-5122
Qaradakhi, Tawar, Gadanec, Laura Kate ORCID: 0000-0002-4801-8061, McSweeney, K, Abraham, JR, Apostolopoulos, Vasso
ORCID: 0000-0001-6788-2771 and Zulli, Anthony
ORCID: 0000-0002-2660-078X
(2020)
The anti-inflammatory effect of taurine on cardiovascular disease.
Nutrients, 12 (9).
pp. 1-23.
ISSN 2072-6643
Qaradakhi, Tawar, Gadanec, Laura Kate ORCID: 0000-0002-4801-8061, McSweeney, Kristen, Tacey, Alexander, Apostolopoulos, Vasso
ORCID: 0000-0001-6788-2771, Levinger, Itamar
ORCID: 0000-0001-9194-2033, Rimarova, Kvetoslava, Egom, Emmanuel E, Rodrigo, L, Kruzliak, P, Kubatka, P and Zulli, Anthony
ORCID: 0000-0002-2660-078X
(2020)
The potential actions of angiotensin-converting enzyme II (ACE2) activator diminazene aceturate (DIZE) in various diseases.
Clinical and Experimental Pharmacology and Physiology.
ISSN 0305-1870
Qaradakhi, Tawar, Gadanec, Laura Kate ORCID: 0000-0002-4801-8061, Tacey, Alexander, Hare, David L, Buxton, Brian F, Apostolopoulos, Vasso
ORCID: 0000-0001-6788-2771, Levinger, Itamar
ORCID: 0000-0001-9194-2033 and Zulli, Anthony
ORCID: 0000-0002-2660-078X
(2019)
The Effect of Recombinant Undercarboxylated Osteocalcin on Endothelial Dysfunction.
Calcified Tissue International.
ISSN 0171-967X
Book Section
McSweeney, Kristen, Gadanec, Laura Kate ORCID: 0000-0002-4801-8061 and Zulli, Anthony
ORCID: 0000-0002-2660-078X
(2022)
Cardiovascular side effects of platinum-based chemotherapy.
In:
Platinum-Based Chemotherapy: Clinical Uses, Efficacy and Side Effects.
Nurgali, K and Abalo Delgado, R, eds.
Cancer Etiology, Diagnosis and Treatments
.
Nova Science Publishers, pp. 175-204.