Article

Ye, K, Traianedes, K, Robins, SA, Choong, Peter F. M and Myers, Damian ORCID: 0000-0002-7569-9907 (2018) Osteochondral repair using an acellular dermal matrix—pilot in vivo study in a rabbit osteochondral defect model. Journal of Orthopaedic Research, 36 (7). pp. 1919-1928. ISSN 0736-0266

Ye, Ken, Felimban, Raed, Traianedes, Kathy, Moulton, Simon E, Wallace, Gordon G, Chung, John, Quigley, Anita, Choong, Peter F. M and Myers, Damian ORCID: 0000-0002-7569-9907 (2014) Chondrogenesis of infrapatellar fat pad derived adipose stem cells in 3D printed chitosan scaffold. PLoS ONE, 9 (6). ISSN 1932-6203

Broadhead, Matthew L, Choong, Peter F. M and Dass, Crispin R (2012) Efficacy of continuously administered PEDF-derived synthetic peptides against osteosarcoma growth and metastasis. Journal of Biomedicine and Biotechnology, 2012. ISSN 1110-7243 (print), 1110-7251 (online)

Broadhead, Matthew L, Clark, Jonathan C. M, Dass, Crispin R, Choong, Peter F. M and Myers, Damian E (2011) Therapeutic targeting of osteoclast function and pathways. Expert Opinion on Therapeutic Targets, 15 (2). pp. 169-181. ISSN 1472-8222

Manalo, Katrina B, Choong, Peter F. M, Becerra, S. Patricia and Dass, Crispin R (2011) Pigment epithelium-derived factor as an anticancer drug and new treatment methods following the discovery of its receptors: A patent perspective. Expert Opinion on Therapeutic Patents, 21 (2). pp. 121-130. ISSN 1354-3776

Choong, Peter F. M, Broadhead, Matthew L, Clark, Jonathan C. M, Myers, Damian E and Dass, Crispin R (2011) The molecular pathogenesis of osteosarcoma: A review. Sarcoma, 2011. pp. 1-12. ISSN 1357-714X

Tan, M, Choong, Peter F. M and Dass, Crispin R (2010) Anti-chondrosarcoma effects of PEDF mediated via molecules important to apoptosis, cell cycling, adhesion and invasion. Biochemical and Biophysical Research Communications, 398 (4). pp. 613-618. ISSN 0006-291X

Broadhead, Matthew L, Becerra, S. Patricia, Choong, Peter F. M and Dass, Crispin R (2010) The applied biochemistry of PEDF and implications for tissue homeostasis. Growth Factors, 28 (4). pp. 280-285. ISSN 0897-7194

Broadhead, Matthew L, Clark, Jonathan C. M, Dass, Crispin R and Choong, Peter F. M (2010) Microarray: an instrument for cancer surgeons of the future? : Surgical science. ANZ Journal of Surgery, 80 (7-8). pp. 531-536. ISSN 1445-1433

Clark, Jonathan C. M, Akiyama, Toru, Dass, Crispin R and Choong, Peter F. M (2010) New clinically relevant, orthotopic mouse models of human chondrosarcoma with spontaneous metastasis. Cancer Cell International, 10. pp. 1-10. ISSN 1475-2867

Dass, Crispin R, Galloway, Stuart J and Choong, Peter F. M (2010) Dz13, a c-jun DNAzyme, is a potent inducer of caspase-2 activation. Oligonucleotides, 20 (3). pp. 137-146. ISSN 1545-4576

Tan, Mei Lin, Dunstan, David E, Friedhuber, Anna M, Choong, Peter F. M and Dass, Crispin R (2010) A nanoparticulate system that enhances the efficacy of the tumoricide Dz13 when administered proximal to the lesion site. Journal of Controlled Release, 144 (2). pp. 196-202. ISSN 0168-3659

Dass, Crispin R, Tan, Mei Lin, Galloway, Stuart J and Choong, Peter F. M (2010) Dz13 induces a cytotoxic stress response with upregulation of E2F1 in tumor cells metastasizing to or from bone. Oligonucleotides, 20 (2). pp. 79-91. ISSN 1545-4576

Dass, Crispin R and Choong, Peter F. M (2010) Sequence-related off-target effect of Dz13 against human tumor cells and safety in adult and fetal mice following systemic administration. Oligonucleotides, 20 (2). pp. 51-60. ISSN 1545-4576

Akiyama, Toru, Choong, Peter F. M and Dass, Crispin R (2010) RANK-Fc inhibits malignancy via inhibiting ERK activation and evoking caspase-3-mediated anoikis in human osteosarcoma cells. Clinical and Experimental Metastasis, 27 (4). pp. 207-215. ISSN 0262-0898

Akiyama, Toru, Dass, Crispin R, Shinoda, Y, Kawano, H, Tanaka, Sakae and Choong, Peter F. M (2010) Systemic RANK-Fc protein therapy is efficacious against primary osteosarcoma growth in a murine model via activity against osteoclasts. Journal of Pharmacy and Pharmacology, 62 (4). pp. 470-476. ISSN 0022-3573

Broadhead, Matthew L, Akiyama, Toru, Choong, Peter F. M and Dass, Crispin R (2010) The pathophysiological role of PEDF in bone diseases. Current Molecular Medicine, 10 (3). pp. 296-301. ISSN 1566-5240

Tan, M, Choong, Peter F. M and Dass, Crispin R (2010) Direct anti-metastatic efficacy by the DNA enzyme Dz13 and downregulated MMP-2, MMP-9 and MT1-MMP in tumours. Cancer Cell International, 10 (9). pp. 1-8. ISSN 1475-2867 (print) 1475-2867 (online)

Tan, M, Choong, Peter F. M and Dass, Crispin R (2010) Anti-Tumour Effect of a Chitosan Delivery System for Doxorubicin. Advanced Materials Research, 93-94 (2010). pp. 703-706. ISSN 1022-6680 (print) 1662-8985 (online)

Tan, M, Choong, Peter F. M and Dass, Crispin R (2010) Recent developments in liposomes, microparticles and nanoparticles for protein and peptide drug delivery. Peptides, 31 (1). pp. 184-193. ISSN 0196-9781

Akiyama, Toru, Dass, Crispin R, Shinoda, Yusuke, Kawano, Hirotaka, Tanaka, Sakae and Choong, Peter F. M (2010) PEDF regulates osteoclasts via osteoprotegerin and RANKL. Biochemical and Biophysical Research Communications, 391 (1). pp. 789-794. ISSN 0006-291X (print) 1090-2104 (online)

Tan, Mei Lin, Friedhuber, Anna M, Dunstan, David E, Choong, Peter F. M and Dass, Crispin R (2010) The performance of doxorubicin encapsulated in chitosan–dextran sulphate microparticles in an osteosarcoma model. Biomaterials, 31 (3). pp. 541-551. ISSN 0142-9612

Broadhead, Matthew L, Clark, Jonathan C. M, Choong, Peter F. M and Dass, Crispin R (2010) Editorial: Making gene therapy for osteosarcoma a reality. Expert Review of Anticancer Therapy, 10 (4). pp. 477-480. ISSN 1473-7140

Akiyama, Toru, Dass, Crispin R and Choong, Peter F. M (2009) Bim-targeted cancer therapy: a link between drug action and underlying molecular changes. Molecular Cancer Therapeutics , 8 (12). pp. 3173-3180. ISSN 1535-7163

Broadhead, Matthew L, Dass, Crispin R and Choong, Peter F. M (2009) In vitro and in vivo biological activity of PEDF against a range of tumors. Expert opinion on therapeutic targets, 13 (12). pp. 1429-1438. ISSN 1744-7631

Hallaj-Nezhadi, Somayeh, Choong, Peter F. M, Lotfipour, Farzaneh and Dass, Crispin R (2009) Gelatin-based delivery systems for cancer gene therapy. Journal of Drug Targeting , 17 (10). pp. 731-738. ISSN 1061-186X

Broadhead, Matthew L, Dass, Crispin R and Choong, Peter F. M (2009) Cancer cell apoptotic pathways mediated by PEDF: prospects for therapy. Trends in Molecular Medicine, 15 (10). pp. 461-467. ISSN 1471-4914

Ta, Hang T, Dass, Crispin R, Larson, Ian, Choong, Peter F. M and Dunstan, David E (2009) A chitosan hydrogel delivery system for osteosarcoma gene therapy with pigment epithelium-derived factor combined with chemotherapy. Biomaterials, 30 (27). pp. 4815-4823. ISSN 0142-9612

Ta, Hang T, Dass, Crispin R, Larson, Ian, Choong, Peter F. M and Dunstan, David E (2009) A chitosan-dipotassium orthophosphate hydrogel for the delivery of Doxorubicin in the treatment of osteosarcoma. Biomaterials, 30 (21). pp. 3605-3613. ISSN 0142-9612

Clark, Jonathan C. M, Dass, Crispin R and Choong, Peter F. M (2009) Development of chondrosarcoma animal models for assessment of adjuvant therapy. ANZ Journal of Surgery, 79 (5). pp. 327-336. ISSN 1445-1433

Ta, Hang T, Dass, Crispin R, Choong, Peter F. M and Dunstan, David E (2009) Osteosarcoma treatment: state of the art. Cancer and Metastasis Reviews, 28 (1-2). pp. 247-263. ISSN 0167-7659

Tan, M, Choong, Peter F. M and Dass, Crispin R (2009) DNAzyme delivery systems: getting past first base. Expert Opinion on Drug Delivery, 6 (2). pp. 127-138. ISSN 1742-5247

Tan, M, Choong, Peter F. M and Dass, Crispin R (2009) Review: Doxorubicin delivery systems based on chitosan for cancer therapy. Journal of Pharmacy and Pharmacology, 61 (2). pp. 131-142. ISSN 0022-3573

Tan, M, Choong, Peter F. M and Dass, Crispin R (2009) Osteosarcoma: conventional treatment vs. gene therapy. Cancer Biology and Therapy, 8 (2). pp. 106-117. ISSN 1538-4047

Tan, M, Choong, Peter F. M and Dass, Crispin R (2009) Cancer, chitosan nanopartides and catalytic nucleic acids. Journal of Pharmacy and Pharmacology, 61 (1). pp. 3-12. ISSN 0022-3573

Dass, Crispin R, Khachigian, Levon M and Choong, Peter F. M (2009) Correction: article on C-Jun and the progression of osteosarcoma: proof in an orthotopic spontaneously metastasizing model. Molecular Cancer Research, 7 (9). p. 1594. ISSN 1541-7786 (print) 1557-3125 (online)

Wei, Yongzhong, Wang, Lei, Clark, Jonathan C. M, Dass, Crispin R and Choong, Peter F. M (2008) Elevated leptin expression in a rat model of fracture and traumatic brain injury. Journal of Pharmacy and Pharmacology, 60 (12). pp. 1667-1672. ISSN 0022-3573

Dass, Crispin R, Galloway, Stuart J, Clark, Jonathan C. M, Khachigian, Levon M and Choong, Peter F. M (2008) Involvement of c-jun in human liposarcoma growth: supporting data from clinical immunohistochemistry and DNAzyme efficacy. Cancer Biology and Therapy, 7 (8). pp. 1297-1301. ISSN 1538-4047

Dass, Crispin R, Friedhuber, Anna M, Khachigian, Levon M, Dunstan, David E and Choong, Peter F. M (2008) Downregulation of c-jun results in apoptosis-mediated anti-osteosarcoma activity in an orthotopic model. Cancer Biology and Therapy, 7 (7). pp. 1033-1036. ISSN 1538-4047

Dass, Crispin R, Khachigian, Levon M and Choong, Peter F. M (2008) c-Jun knockdown sensitizes osteosarcoma to doxorubicin. Molecular Cancer Therapeutics, 7 (7). pp. 1909-1912. ISSN 1535-7163

Dass, Crispin R and Choong, Peter F. M (2008) C-jun: pharmaceutical target for DNAzyme therapy of multiple pathologies. Die Pharmazie, 63 (6). pp. 411-414. ISSN 0031-7144

Clark, Jonathan C. M, Dass, Crispin R and Choong, Peter F. M (2008) A review of clinical and molecular prognostic factors in osteosarcoma. Journal of Cancer Research and Clinical Oncology, 134 (3). pp. 281-297. ISSN 0171-5216

Dass, Crispin R, Choong, Peter F. M and Khachigian, Levon M (2008) DNAzyme technology and cancer therapy: Cleave and let die. Molecular Cancer Therapeutics , 7 (2). pp. 243-251. ISSN 1535-7163

Dass, Crispin R and Choong, Peter F. M (2008) Pigment epithelium-derived factor (PEDF): drug developmental challenges ahead for a budding anti-angiogenic. Die Pharmazie, 63 (1). pp. 4-6. ISSN 0031-7144

Akiyama, Toru, Dass, Crispin R and Choong, Peter F. M (2008) Novel therapeutic strategy for osteosarcoma targeting osteoclast differentiation, bone- resorbing activity and apoptosis pathway. Molecular Cancer Therapeutics, 7 (11). pp. 3461-3469. ISSN 15357163

Dass, Crispin R and Choong, Peter F. M (2008) Cancer angiogenesis: Targeting the heel of Achilles. Journal of Drug Targeting , 16 (6). pp. 449-454. ISSN 1061-186X

Dass, Crispin R and Choong, Peter F. M (2008) Chitosan-mediated orally delivered nucleic acids: A gutful of gene therapy. Journal of Drug Targeting, 16 (4). pp. 257-261. ISSN 1061-186X

Dass, Crispin R and Choong, Peter F. M (2008) Gene therapy for osteosarcoma: steps towards clinical studies. Journal of Pharmacy and Pharmacology, 60 (4). pp. 405-413. ISSN 0022-3573

Dass, Crispin R and Choong, Peter F. M (2008) uPAR mediated anticancer activity of PEDF. Cancer Biology and Therapy, 7 (8). pp. 1262-1270. ISSN 1538-4047

Dass, Crispin R and Choong, Peter F. M (2008) The use of chitosan formulations in cancer therapy. Journal of Microencapsulation, 25 (4). pp. 275-279. ISSN 0265-2048

Dass, Crispin R, Friedhuber, Anna M, Khachigian, Levon M, Dunstan, David E and Choong, Peter F. M (2008) Biocompatible chitosan-DNAzyme nanoparticle exhibits enhanced biological activity. Journal of Microencapsulation, 25 (6). pp. 421-425. ISSN 0265-2048

Dass, Crispin R, Ek, Eugene T. H and Choong, Peter F. M (2008) PEDF as an emerging therapeutic candidate for osteosarcoma. Current Cancer Drug Targets, 8 (8). pp. 683-690. ISSN 1568-0096

Clark, Jonathan C. M, Dass, Crispin R and Choong, Peter F. M (2008) Current and future treatments of bone metastases. Expert Opinion on Emerging Drugs, 13 (4). pp. 609-627. ISSN 1472-8214

Dass, Crispin R, Khachigian, Levon M and Choong, Peter F. M (2008) c-Jun is critical for the progression of osteosarcoma: proof in an orthotopic spontaneously metastasizing model. Molecular Cancer Research, 6 (8). pp. 1289-1292. ISSN 1541-7786

Clark, Jonathan C. M, Thomas, David M, Choong, Peter F. M and Dass, Crispin R (2007) RECK - a newly discovered inhibitor of metastasis with prognostic significance in multiple forms of cancer. Cancer Metastasis Reviews, 26 (3-4). pp. 675-683. ISSN 01677659

Dass, Crispin R and Choong, Peter F. M (2007) GFP expression alters osteosarcoma cell biology. DNA Cell Biology, 26 (8). pp. 599-601. ISSN 1044-5498

Dass, Crispin R and Choong, Peter F. M (2007) Non-viral methods for gene transfer towards osteosarcoma therapy. Journal of Drug Targeting, 15 (3). pp. 184-189. ISSN 1061-186X

Dass, Crispin R and Choong, Peter F. M (2007) Zoledronic acid inhibits osteosarcoma growth in an orthotopic model. Molecular Cancer Therapeutics, 6. pp. 3263-3270. ISSN 1535-7163

Dass, Crispin R, Contreras, Karla G, Dunstan, David E and Choong, Peter F. M (2007) Chitosan microparticles encapsulating PEDF plasmid demonstrate efficacy in an orthotopic metastatic model of osteosarcoma. Biomaterials, 28 (19). pp. 3026-3033. ISSN 01429612

Dass, Crispin R, Ek, Eugene T. H and Choong, Peter F. M (2007) Human xenograft osteosarcoma models with spontaneous metastasis in mice: clinical relevance and applicability for drug testing. Journal of Cancer Research and Clinical Oncology, 133 (3). pp. 193-198. ISSN 0171-5216

Dass, Crispin R, Tran, T. M. N and Choong, Peter F. M (2007) Angiogenesis inhibitors and the need for anti-angiogenic therapeutics. Journal of Dental Research, 86 (10). pp. 927-936. ISSN 0022-0345

Ek, Eugene T. H, Dass, Crispin R, Contreras, Karla G and Choong, Peter F. M (2007) Inhibition of orthotopic osteosarcoma growth and metastasis by multitargeted antitumor activities of pigment epithelium-derived factor. Clinical and Experimental Metastasis, 24 (2). pp. 93-106. ISSN 0262-0898

Ek, Eugene T. H, Dass, Crispin R, Contreras, Karla G and Choong, Peter F. M (2007) Pigment epithelium-derived factor overexpression inhibits orthotopic osteosarcoma growth, angiogenesis and metastasis. Cancer Gene Therapy, 14 (7). pp. 616-626. ISSN 0929-1903

Ek, Eugene T. H, Dass, Crispin R, Contreras, Karla G and Choong, Peter F. M (2007) PEDF-Derived Synthetic Peptides Exhibit Antitumor Activity in an Orthotopic Model of Human Osteosarcoma. Journal of Orthopaedic Research, 25 (12). pp. 1671-1680. ISSN 0736-0266

Pillay, Vinochani, Dass, Crispin R and Choong, Peter F. M (2007) The urokinase plasminogen activator receptor as a gene therapy target for cancer. Trends in Biotechnology, 25 (1). pp. 33-39. ISSN 0167-7799

Ek, Eugene T. H, Dass, Crispin R and Choong, Peter F. M (2006) Commonly used mouse models of osteosarcoma. Critical Reviews in Oncology Hematology, 60 (1). pp. 1-8. ISSN 1040-8428

Ek, Eugene T. H, Dass, Crispin R and Choong, Peter F. M (2006) Pigment epithelium-derived factor: a multimodal tumor inhibitor. Molecular Cancer Therapeutics , 5 (7). pp. 1641-1646. ISSN 1535-7163

Dass, Crispin R and Choong, Peter F. M (2006) Biophysical delivery of peptides: Applicability for cancer therapy. Peptides, 27 (12). pp. 3479-3488. ISSN 0196-9781

Dass, Crispin R and Choong, Peter F. M (2006) Selective gene delivery for cancer therapy using cationic liposomes: In vivo proof of applicability. Journal of Controlled Release, 113 (2). pp. 155-163. ISSN 0168-3659

Dass, Crispin R, Ek, Eugene T. H, Contreras, Karla G and Choong, Peter F. M (2006) A novel orthotopic murine model provides insights into cellular and molecular characteristics contributing to human osteosarcoma. Clinical and Experimental Metastasis , 23 (7-8). pp. 367-380. ISSN 0262-0898

Dass, Crispin R and Choong, Peter F. M (2006) Carrier-mediated delivery of peptidic drugs for cancer therapy. Peptides, 27 (11). pp. 3020-3028. ISSN 0196-9781

Ek, Eugene T. H, Dass, Crispin R and Choong, Peter F. M (2006) PEDF: a potential molecular therapeutic target with multiple anti-cancer activities. Trends in Molecular Medicine, 12 (10). pp. 497-502. ISSN 1471-4914

Dass, Crispin R and Choong, Peter F. M (2006) Targeting of small molecule anticancer drugs to the tumour and its vasculature using cationic liposomes: lessons from gene therapy. Cancer Cell International, 6. ISSN 1475-2867

Dass, Crispin R, Nadesapillai, Anne P. W, Robin, Daniel, Howard, Monique L, Fisher, Jane L, Zhou, Hong and Choong, Peter F. M (2005) Downregulation of uPAR confirms link in growth and metastasis of osteosarcoma. Clinical and Experimental Metastasis, 22 (8). pp. 643-652. ISSN 0262-0898